Cancer Therapy & CUY21
Electroporative Gene Delivery into Tumors
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The CUY21 electroporator range (EDIT and SC) has been used to perform electro-chemotherapy on human skin cancer as a clinical test. Kindly note the article: ‘Electrochemotherapy for digital chondrosarcoma’.
In the article, bleomycine is introduced into the tumor by electroporation.
The CUY21 has also been used to perform electroporation on hepatocellular carcinoma (HCC). Kindly note the paper titled: ‘Electroporation-mediated Interleukin-12 Gene Therapy for Hepatocellular carcinoma in Mice Models‘. In this paper, genes which express IL-12 are transfected into HCC and the growth of HCC is prohibited. In that paper, while a CUY560-5 electrode is used, we would, however, recommend the CUY560-5-0.3 electrode.