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Product Code: SONIDEL SP100

Desc:Sonoporator
Applic:(hover for application)Application:
  • Delivery of plasmids to cells and tissues for gene therapy-based applications and studies.
  • Delivery of nucleic acids such as siRNA, RNAi etc. to cells and tissues for studies on control of gene expression/gene therapy.
  • Delivery of cancer chemotherapeutic agents to impermeable target cells/tissues.
  • Delivery of agents to cells to study metabolic effects.


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Product Code: CUY549G15

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Electrodes for Electroporation
Description:
Gold needle electrode, 15mm tip length, 0.8mmf, 2/pkg

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Electroporation Publications / Protocols

Electroporation Publications and Protocols



Electroporation Publications

CUY21 Electroporator Range 

[2007]
Hepatocyte Growth Factor Promotes Colonic Epithelial Regeneration via Akt Signaling

Masami Kanayama 1, Terumi Takahara 1 (E-mail:
terutaka-tym@umin.ac.jp), Yutaka Yata 1, Feng Xue 1, Eiji Shinno 1, Kazunobu Nonome 1, Hiroshi Kudo 1, Kengo Kawai 1, Takahiko Kudo 1, Yoshiaki Tabuchi 2, Akiharu Watanabe 3 and Toshiro Sugiyama 1
1 Third Department of Internal Medicine, Faculty of Medicine, University of Toyama, Toyama, Japan
2 Life Science Research Center, University of Toyama, Toyama, Japan
3 Kawasaki University of Medical Welfare, Okayama, Japan
American Journal of Physiology - Gastrointest Liver Physiology, 5 April 2007

Identification of XAGE-1 isoforms: predominant expression of XAGE-1b in testis and tumors
Shuichiro Sato 1, 2 (E-mail:
sato-s@md.okayama-u.ac.jp), Yuji Noguchi 1, Nobuya Ohara 3, Akiko Uenaka 1, Michihide Shimono 1, Kazuhiko Nakagawa 1, Fumihito Koizumi 1, Toshiaki Ishida 1, Tadashi Yoshino 3, Yasushi Shiratori 2 and Eiichi Nakayama 1
1 Department of Immunology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan
2 Department of Gastroenterology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan
3 Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan
Cancer Immunity, Volume 7, 5 March 2007

SOCS3 is required to temporally fine-tune photoreceptor cell differentiation
Yoko Ozawa 1, 2, Keiko Nakao 2, 3, 4, Takuya Shimazaki 2, 3, 4, Shigeto Shimmura 1, Toshihide Kurihara 1, 2, Susumu Ishida 1, Akihiko Yoshimura 5, Kazuo Tsubota 1 and Hideyuki Okano 2, 3, 4 (E-mail:
hidokano@sc.itc.keio.ac.jp)
1 Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
2 Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
3 Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Corporation (JST), 4-1-8, Honcho, Kawaguchi, Saitaima 332-0012, Japan
4 Solution Oriented Research for Science and Technology (SORST), Japan Science and Technology Corporation (JST), 4-1-8, Honcho, Kawaguchi, Saitaima 332-0012, Japan
5 Division of Molecular and Cellular Immunology, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan
Developmental Biology, Volume 303, Issue 2, Pages 591-600, 15 March 2007

An Improved Graves' Disease Model Established by Using in Vivo Electroporation Exhibited Long-Term Immunity to Hyperthyroidism in BALB/c Mice
Toshio Kaneda 1, Asako Honda 1, Atsushi Hakozaki 1, Tetsuya Fuse 1, Akihiro Muto 1 and Tadashi Yoshida 1 (E-mail:
tyoshida@hoshi.ac.jp)
1 Department of Pathophysiology, Faculty of Pharmaceutical Science, Hoshi University, Shinagawa, Tokyo 142-0581, Japan
Endocrinology, Volume 148, Issue 5, Pages 2335-2344, May 2007

Therapeutic RNA interference of malignant melanoma by electrotransfer of small interfering RNA targeting Mitf
N Nakai 1, 2, T Kishida 2, M Shin-Ya 2, J Imanishi 2, Y Ueda 3, S Kishimoto 1 and O Mazda 2 (E-mail:
mazda@koto.kpu-m.ac.jp)
1 Department of Dermatology, Kyoto Prefectural University of Medicine, Kyoto, Japan
2 Department of Microbiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
3 Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
Gene Therapy, Volume 14, Number 4, Pages 357-365, February 2007

Design of PCR-amplified DNA fragments for in vivo gene delivery: Size-dependency on stability and transgene expression
Kazuhiro Hirata 1, Makiya Nishikawa 1, Naoki Kobayashi 1, Yuki Takahashi 1 and Yoshinobu Takakura 1 (E-mail:
takakura@pharm.kyoto-u.ac.jp)
1 Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan
Journal of Pharmaceutical Sciences, 23 March 2007

Transfer of spermatogenesis-related cDNAs into eel testis germ-somatic cell coculture pellets by electroporation: Methods for analysis of gene function
C. Miura 1, 2 (E-mail:
miutake@agr.ehime-u.ac.jp), R. Kuwahara 3, T. Miura 1, 2
1 Laboratory of Fish Reproductive Physiology, Faculty of Agriculture, Ehime University, Matsuyama, Ehime, Japan
2 Time Arrow and Biosignaling PRESTO Japan Science and Technology Agency, Kawaguchi, Japan
3 Division of Biological Sciences, Graduate School of Science, Hokkaido University, Sapporo, Japan
Molecular Reproduction and Development, Volume 74, Issue 4, Pages 420-427, April 2007

In-vivo gene transfer into newly hatched chick brain by electroporation
Shinji Yamaguchi 1, Sachiko Katagiri 1, Naoki Hirose 1, Yasuyuki Fujimoto 1, Masahiro Mori 1, Ikuko Fujii-Taira 2, TatsuyaTakano 1, Toshiya Matsushima 3 and Koichi J. Homma 1 (E-mail:
homma-kj@umin.ac.jp, hommakj@pharm.teikyo-u.ac.jp)
1 Faculty of Pharmaceutical Sciences,Teikyo University, Sagamihara-shi, Kanagawa, Japan
2 Futai Special Laboratory, Microbial Chemistry Research Center, Microbial Chemistry Research Foundation, CREST, Japan Science and Technology Agency, Shinagawa-ku, Tokyo, Japan
3 Department of Biology, Faculty of Science, Hokkaido University, Hokkaido, Japan
Neuroreport, Volume 18, Issue 8, Pages 735-739, 28 May 2007

Dual mode of paraxial mesoderm formation during chick gastrulation
Tadahiro Iimura 1, 2, Xuesong Yang 3, Cornelis J. Weijer 3, and Olivier Pourquie 1, 2 (E-mail:
olp@stowers-institute.org)
1 Howard Hughes Medical Institute, Kansas City, MO 64110, USA
2 Stowers Institute for Medical Research, Kansas City, MO 64110, USA
3 Division of Cell and Developmental Biology, Wellcome Trust Biocentre, University of Dundee, Dundee DD1 5EH, United Kingdom
PNAS (Proceedings of the National Academy of Sciences of the United States of America), Volume 104, Number 8, Pages 2744-2749, 20 February 2007

Electrical Stimulation Modulates Fate Determination of Differentiating Embryonic Stem Cells
Masahisa Yamada 1, 2, Kentaro Tanemura 3, 4, Seiji Okada 6, Akio Iwanami 6, Masaya Nakamura 7, Hideaki Mizuno 5, Michiru Ozawa 3, Ritsuko Ohyama-Goto 3, Naohito Kitamura 2, Masako Kawano 1, Kyoko Tan-Takeuchi 1, Chiho Ohtsuka 3, Atsushi Miyawaki 5, Akihiko Takashima 4, Masaharu Ogawa 1, Yoshiaki Toyama 7, Hideyuki Okano 6 and Takashi Kondo 3 (E-mail:
tkondo@brain.riken.jp)
1 Laboratory for Cell Culture Development, Brain Science Institute, Institute of Physical and Chemical Research, Saitama, Japan
2 Yamada Research Unit, Molecular Neuropathology Group; Brain Science Institute, Institute of Physical and Chemical Research, Saitama, Japan
3 Kondo Research Unit, Brain Development Research Group, Brain Science Institute, Institute of Physical and Chemical Research, Saitama, Japan
4 Laboratory for Alzheimer's Disease, Brain Science Institute, Institute of Physical and Chemical Research, Saitama, Japan
5 Laboratory for Cell Function Dynamics, Brain Science Institute, Institute of Physical and Chemical Research, Saitama, Japan
6 Department of Physiology, Keio University School of Medicine, Tokyo, Japan
7 Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan
Stem Cells, Volume 25, Number 3, Pages 562-570, March 2007

Myogenin and the SWI/SNF ATPase Brg1 Maintain Myogenic Gene Expression at Different Stages of Skeletal Myogenesis
Yasuyuki Ohkawa 1, Saori Yoshimura 2, Chiduru Higashi 2, Concetta G. A. Marfella 1, Caroline S. Dacwag 1, Taro Tachibana 2, and Anthony N. Imbalzano 1 (E-mail:
anthony.imbalzano@umassmed.edu)
1 Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01655
2 Department of Bioengineering, Osaka City University, Osaka 558-8585, Japan
JBC (The Journal of Biological Chemistry), Volume 282, Issue 9, Pages 6564-6570, 2 March 2007

Systemic Administration of IL-23 Induces Potent Antitumor Immunity Primarily Mediated through Th1-Type Response in Association with the Endogenously Expressed IL-12
Teruo Kaiga 1, 2, Marimo Sato 1 (E-mail:
marimo@ims.u-tokyo.ac.jp), Hide Kaneda 1, 3, Yoichiro Iwakura 4, Tadatoshi Takayama 2 and Hideaki Tahara 1
1 Department of Surgery and Bioengineering, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan
2 Division of Digestive Surgery, Department of Surgery, Nihon University School of Medicine, Tokyo, Japan
3 Pediatric Surgery, Nihon University School of Medicine, Tokyo, Japan
4 Center of Experimental Medicine, Institute of Medical Science, University of Tokyo, Tokyo, Japan
The Journal of Immunology, Volume 178, Number 12, Pages 7571-7580, June 2007

Early Changes in KCC2 Phosphorylation in Response to Neuronal Stress Result in Functional Downregulation
Hiroaki Wake 1, 2, Miho Watanabe 1, Andrew J. Moorhouse 3, Takashi Kanematsu 4, Shoko Horibe 1, 6 Noriyuki Matsukawa 2, Kiyofumi Asai 5, Kosei Ojika 2, Masato Hirata 4 and Junichi Nabekura 1, 6, 7 (E-mail:
nabekura@nips.ac.jp)
1 Division of Homeostatic Development, National Institute of Physiological Sciences, Okazaki 444-8585, Japan
2 Department of Neurology and Neuroscience, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, Nagoya 467-8601, Japan
3 Department of Physiology and Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia
4 Molecular and Cellular Biochemistry, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan
5 Department of Molecular Neurobiology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan
6 School of Life Science, The Graduate University for Advanced Studies, Hayama 240-0193, Japan
7 Core Research for the Evolutionary Science and Technology, Japan Science and Technology Corporation, Saitama 332-0012, Japan
The Journal of Neuroscience, Volume 27, Issue 7, Pages 1642-1650, 14 February 2007

Cell-autonomous TrkB signaling in presynaptic retinal ganglion cells mediates axon arbor growth and synapse maturation during the establishment of retinotectal synaptic connectivity
Sonya Marshak 1, Angeliki Maria Nikolakopoulou 1, Ron Dirks 2, Gerard J. Martens 2 and Susana Cohen-Cory 1 (E-mail:
scohenco@uci.edu)
1 Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697, USA
2 Department of Molecular Animal Physiology, Nijmegen Center for Molecular Life Sciences, Radboud University Nijmegen, 6525 GA Nijmegen, The Netherlands
The Journal of Neuroscience, Volume 27, Issue 10, Pages 2444-2456, 7 March 2007

Asymmetric Distribution of Prickle-Like 2 Reveals an Early Underlying Polarization of Vestibular Sensory Epithelia in the Inner Ear
Michael R. Deans 1, Dragana Antic 2, 3, Kaye Suyama 2, Matthew P. Scott 2, Jeffrey D. Axelrod 3 and Lisa V. Goodrich 1 (E-mail:
Lisa_Goodrich@hms.harvard.edu)
1 Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115
2 Departments of Developmental Biology, Genetics, and Bioengineering, Howard Hughes Medical Institute
3 Department of Pathology, Stanford University School of Medicine, Stanford, California 94305
The Journal of Neuroscience, Volume 27, Issue 12, Pages 3139-3147, 21 March 2007

Changes in Sef Levels Influence Auditory Brainstem Development and Function
Victoria E. Abraira 1, *, Naomi Hyun 1, *, Andrew F. Tucker 1, *, Donald E. Coling 3, M. Christian Brown 4, Cindy Lu 1, Gregory R. Hoffman 2 and Lisa V. Goodrich 1 (E-mail:
Lisa_Goodrich@hms.harvard.edu)
1 Departments of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115
2 Departments of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115
3 Center for Hearing and Deafness, State University of New York at Buffalo, Buffalo, New York 14260
4 Eaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02115
* These three authors contributed equally to this work.
The Journal of Neuroscience, Volume 27, Issue 16, Pages 4273-4282, 18 April 2007

Zic1 and Zic3 Regulate Medial Forebrain Development through Expansion of Neuronal Progenitors
Takashi Inoue 1, Maya Ota 1, Miyuki Ogawa 1, Katsuhiko Mikoshiba 2 and Jun Aruga 1
1 Laboratory for Comparative Neurogenesis, RIKEN Brain Science Institute, Wako-shi, Saitama 351-0198, Japan
2 Laboratory for Developmental Neurobiology, RIKEN Brain Science Institute, Wako-shi, Saitama 351-0198, Japan
The Journal of Neuroscience, Volume 27, Issue 20, Pages 5461-5473, 16 May 2007


[2006]
Caspase redundancy and release of mitochondrial apoptotic factors characterize interdigital apoptosis
V. Zuzarte-Luis 1, M. T. Berciano 1, M. Lafarga 1 and J. M. Hurle 1, 2 (E-mail:
hurlej@unican.es)
1 Departamento de Anatomia y Biologia Celular, Facultad de Medicina, Universidad de Cantabria, Santander, 39011, Spain
2 Departamento de Anatomia y Biologia Celular, Facultad de Medicina, C/Cardenal Herrera Oria s/n, Santander, 39011, Spain
Apoptosis, Volume 11, Number 5, Pages 701-715, May 2006

Isolation and Characterization of Vasohibin-2 as a Homologue of VEGF-Inducible Endothelium-Derived Angiogenesis Inhibitor Vasohibin
Takumi Shibuya 1, Kazuhide Watanabe 1, 4, Hiroshi Yamashita 1, Kazue Shimizu 1, Hiroki Miyashita 1, Mayumi Abe 1, *, Takuya Moriya 2, Hideki Ohta 3, Hikaru Sonoda 3, Tooru Shimosegawa 4, Koichi Tabayashi 5, Yasufumi Sato 1 (E-mail:
y-sato@idac.tohoku.ac.jp)
1 Department of Vascular Biology, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan
2 Department of Pathology, Tohoku University Hospital, Sendai, Japan
3 Diagnostics Science Division, Shionogi & Co, Ltd, Toyonaka, Japan
4 Department of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan
5 Department of Cardiovascular Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan
* Present address: Department of Nanomedicine, Tokyo Medical and Dental University, Tokyo, Japan
Arteriosclerosis, Thrombosis, and Vascular Biology, Volume 26, Issue 5, Pages 1051-1057, May 2006

Compensation by tumor suppressor genes during retinal development in mice and humans
Stacy L Donovan 1, Brett Schweers 1, Rodrigo Martins 1, Dianna Johnson 2 and Michael A Dyer 1, 2 (E-mail:
michael.dyer@stjude.org)
1 Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA
2 Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
BMC Biology, Volume 4, Issue 14, 3 May 2006

Simultaneous gene transfer of bone morphogenetic protein (BMP) -2 and BMP-7 by in vivo electroporation induces rapid bone formation and BMP-4 expression
Mariko Kawai 1 (E-mail:
marikoka@md.okayama-u.ac.jp), Kazuhisa Bessho 2 (E-mail: bes@kuhp.kyoto-u.ac.jp), Hiroki Maruyama 3 (E-mail: hirokim@med.niigata-u.ac.jp), Jun-ichi Miyazaki 4 (E-mail: jimiyaza@nutri.med.osaka-u.ac.jp) and Toshio Yamamoto 1 (E-mail: ytoshio@md.okayama-u.ac.jp)
1 Department of Oral Morphology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan
2 Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan
3 Division of Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8120, Japan
4 Division of Stem Cell Regulation Research, Osaka University Medical School, Osaka 565-0871, Japan
BMC Musculoskeletal Disorders, Volume 7, Issue 62, 3 August 2006

In vivo Evidence for Radial Migration of Neurons by Long-Distance Somal Translocation in the Developing Ferret Visual Cortex
Victor Borrell 1, * (E-mail:
vborrell@umh.es), Brian K. Kaspar 2, Fred H. Gage 2 and Edward M. Callaway 1
1 Systems Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA
2 Laboratory of Genetics, The Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA
* President address: Instituto de Neurociencias de Alicante, Consejo Superior de Investigaciones Cientificas, Universidad Miguel Hernandez, Sant Joan d'Alacant, Spain
Cerebral Cortex, Volume 16, Number 11, Pages 1571-1583, November 2006

Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development
Daisuke Sakai 1, Takashi Suzuki 1, Noriko Osumi 1 and Yoshio Wakamatsu 2 (E-mail:
wakasama@mail.tains.tohoku.ac.jp)
1 Center for Translational and Advanced Animal Research on Human Diseases, Division of Developmental Neuroscience, Graduate School of Medicine, Tohoku University, Sendai, Miyagi 980-8575, Japan
2 Department of Developmental Neurobiology, Graduate School of Medicine, Tohoku University, Sendai, Miyagi 980-8575, Japan
Development, Volume 133, Issue 7, Pages 1323-1333, April 2006

Pax6-dependent boundary defines alignment of migrating olfactory cortex neurons via the repulsive activity of ephrin A5
Tadashi Nomura 1, Johan Holmberg 2, Jonas Frisen 2 and Noriko Osumi 1, 3 (E-mail:
osumi@mail.tains.tohoku.ac.jp)
1 Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research (CTTAR), Tohoku University School of Medicine, 2-1, Seiryo-machi, Aoba-ku, 980-8575, Japan
2 Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden
3 Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Kawaguchi, 332-0012, Japan
Development, Volume 133, Issue 7, Pages 1335-1345, April 2006

Multidirectional and multizonal tangential migration of GABAergic interneurons in the developing cerebral cortex
Daisuke H. Tanaka 1, Kazunori Maekawa 1, Yuchio Yanagawa 2, Kunihiko Obata 3 and Fujio Murakami 1 (E-mail:
murakami@fbs.osaka-u.ac.jp)
1 Graduate School of Frontier Biosciences, Osaka University, and SORST, Japan
Science and Technology Corporation (JST), Yamadaoka 1-3, Suita, Osaka 560-8531, Japan
2 Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi 371-8511, Japan
3 Neural Circuit Mechanism Group, BSI, RIKEN, Hirosawa 2-1, Wako, 351-0198, Japan
Development, Volume 133, Issue 11, Pages 2167-2176, June 2006

An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation
Shu-Zong Wang 1, Jennifer Dulin 1, Heng Wu 1, Edward Hurlock 1, Sang-Eun Lee 1, Kyle Jansson 1 and Q. Richard Lu 1 (E-mail:
qrichard.lu@utsouthwestern.edu)
1 Center for Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Development, Volume 133, Issue 17, Pages 3389-3398, September 2006

PINCH-1 expression during early avian embryogenesis: Implications for neural crest and heart development
Brad J. Martinsen 1 (E-mail:
marti198@umn.edu), Ann N. Neumann 1, Allison J. Frasier 1, Clare V.H. Baker 2, Catherine E. Krull 3, Jamie L. Lohr 1
1 Department of Pediatrics, Division of Pediatric Cardiology, University of Minnesota School of Medicine, Minneapolis, Minnesota
2 Department of Anatomy, University of Cambridge, Cambridge, England
3 Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan
Developmental Dynamics, Volume 235, Issue 1, Pages 152-162, January 2006

Inhibition of zebrafish fin regeneration using in vivo electroporation of morpholinos against fgfr1 and msxb
Ryan Thummel 1 (E-mail:
thummel.1@nd.edu), Shan Bai 2, Michael P. Sarras Jr 2, Peizhen Song 1, Jeffrey McDermott 1, Jeffrey Brewer 1, Martin Perry 1, Xiaoming Zhang 2, David R. Hyde 3, Alan R. Godwin 1
1 Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas
2 Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas
3 Department of Biological Sciences and Center for Zebrafish Research, University of Notre Dame, Notre Dame, Indiana
Developmental Dynamics, Volume 235, Issue 2, Pages 336-346, February 2006

Basic helix-loop-helix gene Hes6 delineates the sensory hair cell lineage in the inner ear
Dong Qian 1, Kristen Radde-Gallwitz 1, Michael Kelly 1, Bjorn Tyrberg 2, Jaesang Kim 3, Wei-Qiang Gao 4, Ping Chen 1 (E-mail:
pchen@cellbio.emory.edu)
1 Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, USA
2 Burnham Institute, La Jolla, California, USA
3 Division of Molecular Life Sciences, Ewha Womans University, Seoul, Korea
4 Department of Molecular Biology, Genentech, South San Francisco, California, USA
Developmental Dynamics, Volume 235, Issue 6, Pages 1689-1700, June 2006

Electroporation and EGFP labeling of gastrulating quail embryos
Cheng Cui 1, Rusty Lansford 2, Mike B. Filla 1, Charles D. Little 1, Tracey J. Cheuvront 1, Brenda J. Rongish 1 (E-mail:
brongish@kumc.edu)
1 Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas, USA
2 Biology Division, California Institute of Technology, Pasadena, California, USA
Developmental Dynamics, Volume 235, Issue 10, Pages 2802-2810, October 2006

Thyroid hormone-induced expression of a bZip-containing transcription factor activates epithelial cell proliferation during Xenopus larval-to-adult intestinal remodeling
Masayuki Ikuzawa 1, Katsuhiko Shimizu 2, Shigeki Yasumasu 1, Ichiro Iuchi 1, Yun-Bo Shi 3 and Atsuko Ishizuya-Oka 4 (E-mail:
a-oka@nms.ac.jp)
1 Life Science Institute, Sophia University, Chiyoda-ku, Tokyo 102-8554, Japan
2 Yoshizato Project, CLUSTER, Hiroshima Prefectural Institute of Industrial Science and Technology, Higashi-Hiroshima, Hiroshima 739-0046, Japan
3 Laboratory of Gene Regulation and Development, National Institute of Child Health and Human Development, Bethesda, MD 20892-5431, USA
4 Department of Biology, Nippon Medical School, Kawasaki Kanagawa, 211-0063, Japan
Development Genes and Evolution, Volume 216, Number 3, Pages 109-118, March 2006

Role of Gbx2 and Otx2 in the formation of cochlear ganglion and endolymphatic duct
Hiromitsu Miyazaki 1, 2, Toshimitsu Kobayashi 2, Harukazu Nakamura 1, 3, and Jun-ichi Funahashi 1 (E-mail:
junichif@idac.tohoku.ac.jp)
1 Department of Molecular Neurobiology, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan
2 Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan
3 Graduate School of Life Sciences, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan
Development, Growth & Differentiation, Volume 48, Issue 7, Page 429-438, September 2006

Negative feedback predominates over cross-regulation to control ERK MAPK activity in response to FGF signalling in embryos
Terence Gordon Smith 1 (E-mail:
tel_smith@yahoo.co.uk), Maria Karlsson 2, J. Simon Lunn 1, Maxwell C. Eblaghie 1, Iain D. Keenan 2, Elizabeth R. Farrell 1, Cheryll Tickle 1, Kate G. Storey 1 and Stephen M. Keyse 2
1 Division of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
2 Cancer Research UK Molecular Pharmacology Unit, Biomedical Research Centre, Level 5, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, United Kingdom
FEBS Letters, Volume 580, Issue 17, Pages 4242-4245, 24 July 2006

Sustained expression of Epstein-Barr virus episomal vector mediated factor VIII in vivo following muscle electroporation
W. H. Mei 1, G. Q. Qian 1, X. Q. Zhang 1, P. Zhang 1 and J. LU 1 (E-mail:
jianlu@shsmu.edu.cn)
1 Department of Biochemistry and Molecular Biology, School of Medicine, Shanghai JiaoTong University, Shanghai, China
Haemophilia, Volume 12, Issue 3, Page 271-279, May 2006

Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells
Agnes G.S.H. van Rossum 1, Wendy M. Aartsen 1, Jan Meuleman 1, Jan Klooster 2, Anna Malysheva 1, Inge Versteeg 1, Jean-Pierre Arsanto 3, Andre Le Bivic 3 and Jan Wijnholds 1 (Email:
j.wijnholds@nin.knaw.nl)
1 Department of Neuromedical Genetics, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Meibergdreef 47, 1105 BA Amsterdam, The Netherlands
2 Department of Retinal Signal Processing, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Meibergdreef 47, 1105 BA Amsterdam, The Netherlands
3 UMR CNRS 6216, Institute of Developmental Biology of Marseille-Luminy, Faculte des Sciences de Luminy, Case 907, 13288 Marseille Cedex 09, France
Human Molecular Genetics, Volume 15, Issue 18, Pages 2659-2672, 15 September 2006

Activator protein 1-mediated transcriptional regulation strategy sustains long-term expression of a xenogeneic gene product in vivo : An implication for gene therapy targeting congenital protein deficiencies
Shin Sasaki 1, James M. Smith 2, Keiko Takase 1, Kenji Okuda 1, Norihisa Ishii 3 and Fumihiko Takeshita 1 (E-mail:
takesita@yokohama-cu.ac.jp)
1 Department of Molecular Biodefense Research, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan
2 Antibody Systems, Inc. Hurst, Texas 76054, USA
3 Department of Bioregulation, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo 189-0002, Japan
International journal of molecular medicine, Volume 18, Number 2, Pages 289-297, August 2006

L1, beta1 integrin, and cadherins mediate axonal regeneration in the embryonic spinal cord
Murray Blackmore 1 (E-mail:
mblackmore@med.miami.edu) and Paul C. Letourneau 1
1 Department of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455
Journal of Neurobiology, Volume 66, Issue 14, Pages 1564-1583, December 2006

Toll-Like Receptor Adaptor Molecules Enhance DNA-Raised Adaptive Immune Responses against Influenza and Tumors through Activation of Innate Immunity
Fumihiko Takeshita 1 (E-mail:
takesita@yokohama-cu.ac.jp), Toshiyuki Tanaka 1, Tomoko Matsuda 1, Miyuki Tozuka 1, Kouji Kobiyama 1, Sukumar Saha 1, Kiyohiko Matsui 1, Ken J. Ishii 2, Cevayir Coban 2, Shizuo Akira 2, Norihisa Ishii 3, Koichi Suzuki 3, Dennis M. Klinman 4, Kenji Okuda 1 and Shin Sasaki 1
1 Department of Molecular Biodefense Research, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan
2 ERATO, Akira Innate Immunity Program, Japan Science and Technology Agency, Osaka 565-0871, Japan
3 Department of Bioregulation, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo 189-0002, Japan
4 Section of Retroviral Immunology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 208924
Journal of Virology, Volume 80, Number 13, Pages 6218-6224, July 2006

Gene therapy with TRAIL against renal cell carcinoma
Hiroki Matsubara 1, Yoichi Mizutani 1, Fumiya Hongo 1, Hiroyuki Nakanishi 1, Yasunori Kimura 1, So Ushijima 1, Akihiro Kawauchi 1, Takahiro Tamura 2, Tsuneaki Sakata 2 and Tsuneharu Miki 1
1 Department of Urology, Kyoto Prefectural University of Medicine, Kyoto, Japan
2 Shionogi Institute for Medical Science, Osaka, Japan
Molecular Cancer Therapeutics, Volume 5, Issue 9, Pages 21

Collinear activation of Hoxb genes during gastrulation is linked to mesoderm cell ingression
Tadahiro Iimura 1 and Olivier Pourquie 1
1 Howard Hughes Medical Institute and Stowers Institute for Medical Research, 1000 E. 50th Street, Kansas City, Missouri 64110, USA
Nature, Volume 442, Number 7102, Pages 568-571, 3 August 2006

In vivo electroporation in the embryonic mouse central nervous system
Tetsuichiro Saito 1 (E-mail:
tesaito@faculty.chiba-u.jp)
1 Department of Developmental Biology, Graduate School of Medicine Chiba University, Chiba 260-8670, Japan
Nature Protocols, Volume 1, Number 3, Pages 1552-1558, 2006

Chx10 is required to block photoreceptor differentiation but is dispensable for progenitor proliferation in the postnatal retina
Izzy Livne-bar 1, 2, Marek Pacal 1, 2, 4, Melissa C. Cheung 1, 2, Mark Hankin 5, Judy Trogadis 1, 2, Danian Chen 1, 2, Kimberley M. Dorval 1, 2, 4 and Rod Bremner 1, 2, 3, 4 (E-mail:
rbremner@uhnres.utoronto.ca)
1 Toronto Western Research Institute, University Health Network
2 Vision Science Research Program, University of Toronto, Toronto, ON, Canada M5T 2S8
3 Departments of Ophthalmology and Vision Science, University of Toronto, Toronto, ON, Canada M5T 2S8
4 Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada M5T 2S8
5 Department of Anatomy and Neurobiology, Medical College of Ohio, Toledo, OH 43614
PNAS (Proceedings of the National Academy of Sciences of the United States of America), Volume 103, Number 13, Pages 4988-4993, 28 Mar 2006

Analysis on the Molecular Species and Concentration of Circulating ADAMTS13 in Blood
Kenji Soejima 1 (E-mail:
soejima@kaketsuken.or.jp), Hitomi Nakamura 1, Masaki Hirashima 1, Wataru Morikawa 1, Chikateru Nozaki 1 and Tomohiro Nakagaki 1
1 Research Department 1, The Chemo-Sero-Therapeutic Research Institute, Kyokushikawabe, Kikuchi, Kumamoto 869-1298
The Journal of Biochemistry, Volume 139, Issue 1, Pages 147-154, January 2006

Mouse Disabled1 (DAB1) Is a Nucleocytoplasmic Shuttling Protein
Takao Honda 1 and Kazunori Nakajima 1, 2 (E-mail:
kazunori@sc.itc.keio.ac.jp)
1 Department of Anatomy, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
2 Department of Molecular Neurobiology, Institute of DNA Medicine, Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan
JBC (The Journal of Biological Chemistry), Volume 281, Issue 50, Pages 38951-38965, 15 December 2006

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
Hajime Kanda 1, Sanshiro Tateya 1, Yoshikazu Tamori 1 (E-mail:
tamori@med.kobe-u.ac.jp), Ko Kotani 1, Ken-ichi Hiasa 2, Riko Kitazawa 3, Sohei Kitazawa 3, Hitoshi Miyachi 4, Sakan Maeda 3, Kensuke Egashira 2 and Masato Kasuga 1
1 Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
2 Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
3 Department of Biomedical Informatics, Kobe University Graduate School of Medicine, Kobe, Japan
4 Laboratory for Animal Resources and Genetic Engineering, Center for Developmental Biology (CDB), Institute of Physical and Chemical Research (RIKEN), Kobe, Japan
JCI (The Journal of Clinical Investigation), Volume 116, Issue 6, Pages 1494-1505, June 2006

VEGF 164 gene transfer by electroporation improves diabetic sensory neuropathy in mice
Tatsufumi Murakami 1 (E-mail:
tatsum@med.kawasaki-m.ac.jp), Makiko Arai 2, Yoshihide Sunada 1, Akihiro Nakamura 2
1 Division of Neurology, Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Japan
2 Department of Clinical Pharmacy, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Japan
The Journal of Gene Medicine, Volume 8, Issue 6, Pages 773-781, July 2006

Radial Migration of Superficial Layer Cortical Neurons Controlled by Novel Ig Cell Adhesion Molecule MDGA1
Akihide Takeuchi 1 and Dennis D. M. O'Leary 1
1 Molecular Neurobiology Laboratory, The Salk Institute, La Jolla, California 92037, USA
The Journal of Neuroscience, Volume 26, Issue 17, Pages 4460-4464, 26 April 2006

Necdin Promotes GABAergic Neuron Differentiation in Cooperation with Dlx Homeodomain Proteins
Takaaki Kuwajima 1, Isao Nishimura 1 and Kazuaki Yoshikawa 1 (E-mail:
yoshikaw@protein.osaka-u.ac.jp)
1 Laboratory of Regulation of Neuronal Development, Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan
The Journal of Neuroscience, Volume 26, Issue 20, Pages 5383-5392, 17 May 2006

Brain-Derived Neurotrophic Factor Participates in Determination of Neuronal Laminar Fate in the Developing Mouse Cerebral Cortex
Hidefumi Fukumitsu 1, Masanari Ohtsuka 1, Rina Murai 1, Hiroyuki Nakamura 2, Kazuo Itoh 2 and Shoei Furukawa 1 (E-mail:
furukawa@gifu-pu.ac.jp)
1 Laboratory of Molecular Biology, Gifu Pharmaceutical University, Gifu 502-8585, Japan
2 Department of Morphological Neuroscience, Gifu University Graduate School of Medical Science, Gifu 501-1194, Japan
The Journal of Neuroscience, Volume 26, Issue 51, Pages 3218-13230, 20 December 2006

Gene Expression Analysis of Ectopic Bone Formation Induced by Electroporatic Gene Transfer of BMP4
Satoshi Kotajima 1, Koshi N. Kishimoto 1, Munenori Watanuki 1, Masahito Hatori 1 and Shoichi Kokubun 1
1 Department of Orthopaedic surgery, Tohoku University School of Medicine, Sendai, Japan
Upsala Journal of Medical Sciences, Volume 111, Number 2, Pages 231-242, 2006

Multivalent DNA vaccine protects mice against pulmonary infection caused by Pseudomonas aeruginosa
Sukumar Saha 1, Fumihiko Takeshita 1, Shin Sasaki 1, Tomoko Matsuda 1, Toshiyuki Tanaka 1, Miyuki Tozuka 1, Keiko Takase 1, Tetsuya Matsumoto 2, Katsuji Okuda 3, Norihisa Ishii 4, Keizo Yamaguchi 2, Dennis M. Klinman 5, Ke-Qin Xin 1, Kenji Okuda 1 (E-mail:
kokuda@med.yokohama-cu.ac.jp)
1 Department of Molecular Biodefense Research, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan
2 Department of Microbiology, Toho University School of Medicine, Tokyo 143-0015, Japan
3 Department of Microbiology, Tokyo Dental University, Chiba 261-0011, Japan
4 Department of Bioregulation, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo 189-0002, Japan
5 Section of Retroviral Immunology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Vaccine, Volume 24, Issues 37-39, Pages 6240-6249, 11 September 2006


[2005]
Production of research-grade antibody by in vivo electroporation of DNA-encoding target protein
Fumiaki Okahara 1, 2, Kouichi Itoh 1, 3, Michihiro Ebihara 4, Masao Kobayashi 4, Hiroki Maruyama 5, Yasunori Kanaho 1 and Tomohiko Maehama 1 (E-mail:
tmaehama@rinshoken.or.jp)
1 Department of Pharmacology, Tokyo Metropolitan Institute of Medical Science, Tokyo 113-8613, Japan
2 Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, Tokyo 192-0397, Japan
3 Laboratory of Molecular Pharmacology, Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences at Kagawa Campus, Tokushima Bunri University, Kagawa 769-2193, Japan
4 Division of Biochemistry, BEX Co. Ltd., Tokyo 173-0004, Japan
5 Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8120, Japan
Analytical Biochemistry, Volume 336, Issue 1, Pages 138-140, 1 January 2005

Use of local electroporation enhances methotrexate effects with minimum dose in adjuvant-induced arthritis
Masahiro Tada 1 (E-mail:
m-tada@med.osaka-cu.ac.jp), Kentaro Inui 1, Tatsuya Koike 1 and Kunio Takaoka 1
1 Osaka City University, Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan
Arthritis & Rheumatism, Volume 52, Issue 2, Pages 637-641, February 2005

Electro-transfer of small interfering RNA ameliorated arthritis in rats
Atsuo Inoue 1, Kenji A. Takahashi 1 (E-mail:
t-keji@mbox.kyoto-inet.or.jp), Osam Mazda 2, Ryu Terauchi 1, Yuji Arai 1, Tsunao Kishida 2, 3, Masaharu Shin-Ya 2, Hidetsugu Asada 2, Toru Morihara 1, Hitoshi Tonomura 1, Suzuyo Ohashi 1, Yoshiteru Kajikawa 1, Yutaka Kawahito 4, Jiro Imanishi 2, Mitsuhiro Kawata 5, Toshikazu Kubo 1
1 Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
2 Department of Microbiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
3 Louis Pasteur Center for Medical Research, Kyoto 606-8225, Japan
4 Department of Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
5 Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
Biochemical and Biophysical Research Communications, Volume 336, Issue 3, Pages 903-908, 28 October 2005

G Protein betagamma Subunits and AGS3 Control Spindle Orientation and Asymmetric Cell Fate of Cerebral Cortical Progenitors
Kamon Sanada 1 and Li-Huei Tsai 1, 2 (E-mail:
li-huei_tsai@hms.harvard.edu)
1 Department of Pathology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115
2 Howard Hughes Medical Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115
Cell, Volume 122, Issue 1, Pages 119-131, 15 July 2005

XAGE-1 Expression in Non-Small Cell Lung Cancer and Antibody Response in Patients
Kazuhiko Nakagawa 1, 2, Yuji Noguchi 1, Akiko Uenaka 1, Shuichiro Sato 1, Hideo Okumura 1, 2, Motoyuki Tanaka 1, Michihide Shimono 1, Ali Mohamed Ali Eldib 1, Toshiro Ono 1, Nobuya Ohara 3, Tadashi Yoshino 3, Kazuki Yamashita 4, Tsukasa Tsunoda 4, Motoi Aoe 2, Nobuyoshi Shimizu 2 and Eiichi Nakayama 1 (E-mail:
nakayama@md.okayama-u.ac.jp)
1 Departments of Immunology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
2 Departments of Oncology and Thoracic Surgery Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
3 Departments of Pathology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
4 Department of Surgery, Division of Gastroenterology, Kawasaki Medical School, Kurashiki, Japan
Clinical Cancer Research, Volume 11, Issue 15, Pages 5496-5503, 1 August 2005

Progenitors resume generating neurons after temporary inhibition of neurogenesis by Notch activation in the mammalian cerebral cortex
Ken-ichi Mizutani 1 and Tetsuichiro Saito 1, * (E-mail:
tesaito@frontier.kyoto-u.ac.jp)
1 Department of Development and Differentiation, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan
* Present address: Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan
Development, Volume 132, Issue 6, Pages 1295-1304, March 2005

Commissural neuron identity is specified by a homeodomain protein, Mbh1, that is directly downstream of Math1
Rie Saba 1, Jane E. Johnson 2 and Tetsuichiro Saito 1 (E-mail:
tesaito@frontier.kyoto-u.ac.jp)
1 Department of Development and Differentiation, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan
2 Center for Basic Neuroscience, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9111, USA
Development, Volume 132, Issue 9, Pages 2147-2155, May 2005

Notch signaling functions as a binary switch for the determination of glandular and luminal fates of endodermal epithelium during chicken stomach development
Yoshimasa Matsuda 1, Yoshio Wakamatsu 2, Jun Kohyama 3, Hideyuki Okano 3, Kimiko Fukuda 1 and Sadao Yasugi 1 (E-mail:
yasugi-sadao@c.metro-u.ac.jp)
1 Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, 1-1 Minamiohsawa, Hachiohji, Tokyo 192-0397, Japan
2 Department of Developmental Neurobiology, Graduate School of Medicine, Tohoku University, Sendai, Miyagi 980-8575, Japan
3 Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan
Development, Volume 132, Issue 12, Pages 2783-2793, June 2005

Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor
Atsushi Sawada 1, Yuriko Nishizaki 2, Hiroko Sato 1, Yukari Yada 1, Rika Nakayama 3, Shinji Yamamoto 1, Noriyuki Nishioka 1, Hisato Kondoh 2 and Hiroshi Sasaki 1 (E-mail:
sasaki@cdb.riken.jp),
1 Laboratory for Embryonic Induction, RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan
2 Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan
3 Laboratory for Animal Resources and Genetic Engineering (LARGE), RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan
Development, Volume 132, Issue 21, Pages 4719-4729, November 2005

Ex ovo electroporation for gene transfer into older chicken embryos
Jiankai Luo 1 (E-mail:
tluo@mti.uni-jena.de) and Christoph Redies 1
1 Institute of Anatomy I, Friedrich Schiller University, Jena, Germany
Developmental Dynamics, Volume 233, Issue 4, Pages 1470-1477, August 2005

Regulation of Slug transcription in embryonic ectoderm by beta-catenin-Lef/Tcf and BMP-Smad signaling
Daisuke Sakai 1, Yasuko Tanaka 2, Yukinori Endo 1, Noriko Osumi 1, Harumasa Okamoto 2 and Yoshio Wakamatsu 3 (E-mail:
wakasama@mail.tains.tohoku.ac.jp)
1 Center for Translational and Advanced Animal Research on Human Diseases, Division of Developmental Neuroscience, Graduate School of Medicine, Tohoku University, Sendai, Miyagi 980-8575, Japan
2 AIST, Tsukuba, Japan
3 Department of Developmental Neurobiology, Graduate School of Medicine, Tohoku University, Sendai, Miyagi 980-8575, Japan
Development, Growth & Differentiation, Volume 47, Issue 7, Pages 471-482, September 2005

Birth-date-dependent segregation of the mouse cerebral cortical neurons in reaggregation cultures
Itsuki Ajioka 1, 2 and Kazunori Nakajima 1, 2, 3 (E-mail:
kazunori@sc.itc.keio.ac.jp)
1 Department of Anatomy, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
2 Department of Molecular Neurobiology, Institute of DNA Medicine, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo 105-8461, Japan
3 Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Corporation (JST), 4-1-8 Honmachi, Kawaguchi, Saitama 332-0012, Japan
European Journal of Neuroscience, Volume 22, Issue 2, Pages 331-342, July 2005

FGF8 initiates inner ear induction in chick and mouse
Raj K. Ladher 1, 2, *, (E-mail
raj-ladher@cdb.riken.go.jp), Tracy J. Wright 4, *, Anne M. Moon 2, 5, Suzanne L. Mansour 2, 4 and Gary C. Schoenwolf 2, 3
1 Sensory Development, Riken Center for Developmental Biology, Chuo-ku, Kobe 650-0047, Japan
2 Department of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, Utah 84132-3401, USA
3 Department of Children's Health Research Center, University of Utah School of Medicine, Salt Lake City, Utah 84132-3401, USA
4 Department of Human Genetics, University of Utah, Salt Lake City, Utah 84112-5330, USA
5 Department of Program in Human Molecular Biology and Genetics, University of Utah, Salt Lake City, Utah 84112-5330, USA
* These authors contributed equally to the study
Genes & Development, Volume 19, Issue 5, Pages 603-613, 1 March 2005

Generation of antitumor immunity against large colon tumors by repeated runs of electrochemotherapy
Yoshio Gunji 1 (E-mail:
gunjim9@faculty.chiba-u.jp), Masaya Uesato 1, Shinichi Miyazaki 1, Hideaki Shimada 1, Hisahiro Matsubara 1, Yoshihiro Nabeya 1, Keiji Kouda 1, Harufumi Makino 1, Teruo Kouzu 1 and Takenori Ochiai 1
1 Department of Frontier Surgery (M9), Graduate School of Medicine, Chiba University School of Medicine, Chiba, Japan
Hepatogastroenterology, Volume 52, Number 63, Pages 770-774, May-June 2005

The Pax6 isoform bearing an alternative spliced exon promotes the development of the neural retinal structure
Noriyuki Azuma 1, 2 (E-mail:
azuma-n@ncchd.go.jp), Keiko Tadokoro 2, Astuko Asaka 2, Masao Yamada 2, Yuki Yamaguchi 3, Hiroshi Handa 3, Satsuki Matsushima 4, Takashi Watanabe 4, Shinichi Kohsaka 5, Yasuyuki Kida 6, Tomoki Shiraishi 6, Toshihiko Ogura 6, Kenji Shimamura 7, 8 and Masato Nakafuku 7, 9
1 Department of Ophthalmology, National Center for Child Health and Development, Tokyo 157-8535, Japan
2 Department of Genetics, National Research Institute for Child Health and Development, Tokyo 154-8567, Japan
3 Department of Biological Information, Tokyo Institute of Technology, Graduate School of Bioscience and Biotechnology, Yokohama, 226-8501, Japan
4 Department of Laboratory Medicine, Kyorin University School of Medicine, Tokyo 181-8611, Japan
5 National Institute of Neuroscience, Tokyo 187-8502, Japan
6 Department of Developmental Neurobiology, Institute of Development, Aging and Cancer, Sendai 980-8575, Japan
7 Department of Neuroscience, University of Tokyo Graduate School of Medicine, Tokyo 113-0033, Japan
8 Division of Morphogenesis, Department of Embroyogenesis, Institute of Molecular Embryology and Genetics, Kumamoto University, Honjo 2-2-1, Kumamoto 860-0811, Japan
9 Division of Developmental Biology, Cincinnati Children's Hospital Research Foundation, Cincinnati, OH 45229, USA
Human Molecular Genetics, Volume 14, Number 6, Pages 735-745, 15 March 2005

Transdifferentiation of the retinal pigment epithelia to the neural retina by transfer of the Pax6 transcriptional factor
Noriyuki Azuma 1, 2 (E-mail:
azuma-n@ncchd.go.jp), Keiko Tadokoro 2, Astuko Asaka 2, Masao Yamada 2, Yuki Yamaguchi 3, Hiroshi Handa 3, Satsuki Matsushima 4, Takashi Watanabe 4, Yasuyuki Kida 5, Toshihiko Ogura 5, Masaaki Torii 6, Kenji Shimamura 6, 7 and Masato Nakafuku 6, 8
1 Department of Ophthalmology, National Center for Child Health and Development, Tokyo 157-8535, Japan
2 Department of Genetics, National Research Institute for Child Health and Development, Tokyo 154-8567, Japan
3 Department of Biological Information, Tokyo Institute of Technology, Graduate School of Bioscience and Biotechnology, Yokohama 226-8501, Japan
4 Department of Clinical Research Medicine, Kyorin University School of Medicine, Tokyo 181-8611, Japan
5 Department of Developmental Neurobiology, Institute of Development, Aging and Cancer, Sendai 980-8575, Japan
6 Department of Neuroscience, University of Tokyo Graduate School of Medicine, Tokyo 113-0033, Japan
7 Division of Morphogenesis, Department of Embryogenesis, Institute of Molecular Embryology and Genetics, Kumamoto University, Honjo 2-2-1, Kumamoto 860-0811, Japan
8 Division of Developmental Biology, Cincinnati Children's Hospital Research Foundation, Cincinnati, OH 45229, USA
Human Molecular Genetics, Volume 14, Number 8, Pages 1059-1068, 15 April 2005

Immune deficiency enhances expression of recombinant human antibody in mice after nonviral in vivo gene transfer
Kohji Kitaguchi 1, Mikako Toda 1, Masataka Takekoshi 2, Fumiko Maeda 2, tatsuo Muramatsu 1 and Atsushi Murai 1
1 Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601
2 Department of Molecular Life Science, Tokai University School of Medicine, Bohseidai, Isehara 259-1193, Japan
International Journal of Molecular Medicine, Volume 16, Number 4, Pages 683-688, October 2005

Mutated-leptin gene transfer induces increases in body weight by electroporation and hydrodynamics-based gene delivery in mice
Lan Xiang 1, Atsushi Murai 1 and Tatsuo Muramatsu 1
1 Laboratory of Animal Nutrition, Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan
International Journal of Molecular Medicine, Volume 16, Number 6, Pages 1015-1020, December 2005

Cancer gene therapy using in vivo electroporation of Flt3-ligand
Kazuya Shimao 1, 2, Takuya Takayama 1 (E-mail:
takayama@ims.u-tokyo.ac.jp), Katsuhisa Enomoto 1, Tetsuya Saito 1, Shigenori Nagai 1, Jun-ichi Miyazaki 3, Kenji Ogawa 2 and Hideaki Tahara 1
1 Department of Surgery and Bioengineering Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan
2 Department of Surgery, Tokyo Women Medical College Daini Hospital, Tokyo, Japan
3 Division of Stem Cell Regulation Research, G6, Osaka University Medical School, Osaka, Japan
International Journal of Oncology, Volume 27, Number 2, Pages 457-463, August 2005

Novel kruppel-like factor is induced by neuronal activity and by sensory input in the central nervous system of the terrestrial slug Limax valentianus
Satoshi Fukunaga 1, Ryota Matsuo 1, 2 (E-mail:
matsuor@kph.bunri-u.ac.jp), Syohei Hoshino 1 and Yutaka Kirino 1
1 Laboratory of Neurobiophysics, School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
2 Laboratory of Functional Biology, Faculty of Pharmaceutical Sciences at Kagawa Campus, Tokushima Bunri University, Shido, Sanuki-City, Kagawa 769-2193, Japan
Journal of Neurobiology, Volume 66, Issue 2, Pages 169-181, 5 February 2006

Matrix metalloproteinase expression and function during fin regeneration in zebrafish: Analysis of MT1-MMP, MMP2 and TIMP2B
Shan Bai 1, *, Ryan Thummel 2, Alan R. Godwin 2, Hideaki Nagase 1, 3, Yoshifumi Itoh 3, Li Li 1, Richard Evans 3, Jeffrey McDermott 2, Motoharu Seiki 4, Michael P. Sarras Jr. 5 (E-mail:
michael.sarras@rosalindfranklin.edu)
1 Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS, 66160 USA
2 Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS, 66160, USA
3 Kennedy Institute of Rheumatology/Division, Faculty of Medicine, Imperial College, London, London, UK
4 Division of Cancer Cell Research, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8630, Japan
5 Department of Cell Biology and Anatomy, Rosalind Franklin University of Medicine and Science/The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, United States
* President address: Department of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Matrix Biology, Volume 24, Issue 4, Pages 247-260, June 2005

Evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1
Fanie Barnabe-Heider 1, 5, Julie A. Wasylnka 1, 2, Karl J.L. Fernandes 1, 2, Christian Porsche 6, Michael Sendtner 6, David R. Kaplan 2, 3, 5 and Freda D. Miller 1, 3, 4, 5 (E-mail:
fredam@sickkids.ca)
1 Developmental Biology, University of Toronto, Toronto M5G 1X8, Canada
2 Cancer Research, Hospital for Sick Children, University of Toronto, Toronto M5G 1X8, Canada
3 Department of Molecular and Medical Genetics, University of Toronto, Toronto M5G 1X8, Canada
4 Department of Physiology, University of Toronto, Toronto M5G 1X8, Canada
5 Department of Neurology and Neurosurgery, McGill University, Montreal H3A 2B4, Canada
6 Institute of Clinical Neurobiology, University of Wuerzburg, Wuerzburg 97080, Germany
Neuron, Volume 48, Issue 2, Pages 253-265, 20 October 2005

cAMP-responsive element in TATA-less core promoter is essential for haploid-specific gene expression in mouse testis
Pranee Somboonthum 1, Hiroshi Ohta 1, Shuichi Yamada 2, Masayoshi Onishi 1, Akiko Ike 1, Yoshitake Nishimune 1 and Masami Nozaki 1 (E-mail:
mnozaki@biken.osaka-u.ac.jp)
1 Department of Science for Laboratory Animal Experimentation, Research Institute for Microbial Diseases, Osaka University Suita, Osaka 565-0871, Japan
2 Department of Cell Biology, Institute for Virus Research, Kyoto University Kyoto 606-8507, Japan
Nucleic Acids Research, Volume 33, Issue 10, Pages 3401-3411, 10 June 2005

Tissue-Specific Characteristics of in Vivo Electric Gene: Transfer by Tissue and Intravenous Injection of Plasmid DNA
Oranuch Thanaketpaisarn 1, Makiya Nishikawa 2 (E-mail:
makiya@pharm.kyoto-u.ac.jp), Fumiyoshi Yamashita 1 and Mitsuru Hashida 1
1 Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan
2 Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan
Pharmaceutical Research, Volume 22, Number 6, Pages 883-891, June 2005

Human BMP-2 gene transfer using transcutaneous in vivo electroporation induced both intramembranous and endochondral ossification
Mariko Kawai 1 (E-mail
marikoka@md.okayama-u.ac.jp), Kazuhisa Bessho 2, Hiroki Maruyama 3, Jun-Ichi Miyazaki 4 and Toshio Yamamoto 1
1 Department of Oral Morphology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
2 Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
3 Division of Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
4 Division of Stem Cell Regulation Research, Osaka University, School of Medicine, Osaka, Japan
The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology, Volume 287A, Issue 2, Pages 1264-1271, December 2005

Neuronal generation, migration, and differentiation in the mouse hippocampal primoridium as revealed by enhanced green fluorescent protein gene transfer by means of in utero electroporation
Eiko Nakahira (E-mail:
nakahira@ncnp.go.jp) and Shigeki Yuasa
Department of Ultrastructural Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo 187-8502, Japan
The Journal of Comparative Neurology, Volume 483, Issue 3, Pages 329-340, 14 March 2005

Activity Dependence of Cortical Axon Branch Formation: A Morphological and Electrophysiological Study Using Organotypic Slice Cultures
Naofumi Uesaka 1, Satoshi Hirai 1, Takuro Maruyama 1, Edward S. Ruthazer 2 and Nobuhiko Yamamoto 1
1 Neuroscience Laboratories, Graduate School of Frontier Biosciences, Osaka University, Osaka 565-0871, Japan
2 Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, H3A 2B4 Canada
The Journal of Neuroscience, Volume 25, Issue 1, Pages 1-9, 5 January 2005

The Caudal Migratory Stream: A Novel Migratory Stream of Interneurons Derived from the Caudal Ganglionic Eminence in the Developing Mouse Forebrain
Masato Yozu 1, Hidenori Tabata 1 and Kazunori Nakajima 1, 2
1 Department of Anatomy, Keio University School of Medicine, Tokyo 160-8582, Japan
2 Department of Molecular Neurobiology, Institute of DNA Medicine, Jikei University School of Medicine, Tokyo 105-8461, Japan
The Journal of Neuroscience, Volume 25, Issue 31, Pages 7268-7277, 3 August 2005

Role of Fabp7, a Downstream Gene of Pax6, in the Maintenance of Neuroepithelial Cells during Early Embryonic Development of the Rat Cortex
Yoko Arai 1, Nobuo Funatsu 2, Keiko Numayama-Tsuruta 1, Tadashi Nomura 1, Shun Nakamura 2 and Noriko Osumi 1, 3 (E-mail:
osumi@mail.tains.tohoku.ac.jp)
1 Division of Developmental Neuroscience, Department of Functional Genomics, Center for Translational and Advanced Animal Research, Tohoku University School of Medicine, Aoba-ku, Sendai 980-8575, Japan
2 Division of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo 187-8502, Japan
3 Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Kawaguchi, 332-0012, Japan
The Journal of Neuroscience, Volume 25, Issue 42, Pages 9752-9761, 19 October 2005

CCAAT/Enhancer-Binding Protein Phosphorylation Biases Cortical Precursors to Generate Neurons Rather Than Astrocytes In Vivo
Annie Paquin 1, 2, 3, Fanie Barnabe-Heider 1, 2, 6, Ryoichiro Kageyama 7 and Freda D. Miller 1, 2, 3, 4, 5, 6
1 Developmental Biology, Hospital for Sick Children, University of Toronto, Toronto, Canada M5G 1X8
2 Brain and Behavior Groups, Hospital for Sick Children, University of Toronto, Toronto, Canada M5G 1X8
3 Institute of Medical Sciences, University of Toronto, Toronto, Canada M5G 1X8
4 Departments of Molecular and Medical Genetics, University of Toronto, Toronto, Canada M5G 1X8
5 Departments of Physiology, University of Toronto, Toronto, Canada M5G 1X8
6 Department of Neurology and Neurosurgery, McGill University, Montreal, Canada H3A 2B4
7 Virology Institute, Kyoto University, Kyoto 606-8507, Japan
The Journal of Neuroscience, Volume 25, Issue 46, Pages 10747-10758, 16 November 2005


[2004]
Monocyte Chemoattractant Protein-1 Is an Essential Inflammatory Mediator in Angiotensin II-Induced Progression of Established Atherosclerosis in Hypercholesterolemic Mice
Weihua Ni 1, Shiro Kitamoto 1, Minako Ishibashi 1, Makoto Usui 1, Shujiro Inoue 1, Ken-ichi Hiasa 1, Qingwei Zhao 1, Ken-ichi Nishida 2, Akira Takeshita 1, Kensuke Egashira 1 (E-mail:
egashira@cardiol.med.kyushu-u.ac.jp)
1 Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
2 New Product Research Laboratories, Dai-ichi Pharmaceutical Company, Tokyo, Japan
Arteriosclerosis, Thrombosis, and Vascular Biology, Volume 24, Issue 3, Pages 534-539, March 2004

In vivo gene transfer into the adult honeybee brain by using electroporation
Takekazu Kunieda 1 and Takeo Kubo 1 (E-mail:
stkubo@mail.ecc.u-tokyo.ac.jp)
1 Department of Biological Sciences, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Biochemical and Biophysical Research Communications, Volume 318, Issue 1, Pages 25-31, 21 May 2004

Techniques of signal generation required for electropermeabilization.
Survey of electropermeabilization devices
Marko Puc 1, Selma Corovic 1, Karel Flisar 1, Marko Petkovsek 1, Janez Nastran 1 and Damijam Miklavcic 1
1 University of Ljubljana, Faculty of Electrical Engineering, Trzaska 25, SI-1000 Ljubljana, Slovenia
Bioelectrochemistry, Volume 64, Issue 2, Pages 113-124, September 2004

Synergistic antitumor effect of antiangiogenic factor genes on colon 26 produced by low-voltage electroporation
Masaya Uesato 1, Yoshio Gunji 1 (E-mail:
gunjim9@faculty.chiba-u.jp), Takeshi Tomonaga 2, Shinichi Miyazaki 1, Tooru Shiratori 1, Hisahiro Matsubara 1, Teruo Kouzu 3, Hideaki Shimada 1, Fumio Nomura 2 and Takenori Ochiai 1
1 Department of Academic Surgery (M9), Graduate School of Medicine, Chiba University 1-8-1, Inohana, Chuou-ku, Chiba-city, Chiba 260-8670, Japan
2 Department of Molecular Diagnosis (F8), Graduate School of Medicine, Chiba University 1-8-1, Inohana, Chuou-ku, Chiba-city, Chiba 260-8670, Japan
3 Department of Endoscopic Diagnostics and Therapeutics, Graduate School of Medicine, Chiba University 1-8-1, Inohana, Chuou-ku, Chiba-city, Chiba 260-8670, Japan
Cancer Gene Therapy, Volume 11, Number 9, Pages 625-632, September 2004

Inhibition of RL male 1 tumor growth in BALB/c mice by introduction of the RLakt gene coding for antigen recognized by cytotoxic T-lymphocytes and the GM-CSF gene by in vivo electroporation
Motoyuki Tanaka 1, 2, Masaharu Yamada 3, Toshiro Ono 1, Yuji Noguchi 1, Akiko Uenaka 1, Seisuke Ota 1, 2, Hidenori Hata 1, Mine Harada 2, 4, Mitsune Tanimoto 2 and Eiichi Nakayama 1 (E-mail:
nakayama@md.okayama-u.ac.jp)
1 Department of Immunology, Okayama University Graduate School of Medicine and Dentistry, 2-5-1 Shikata-cho, Okayama 700-8558, Japan
2 Department of Internal Medicine II, Okayama University Graduate School of Medicine and Dentistry, 2-5-1 Shikata-cho, Okayama 700-8558, Japan
3 Department of Surgery and Clinical Oncology, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita 565-0871, Japan
4 Department of Medicine and Biosystemic Science, Kyushu Uni-versity Faculty of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582
Cancer Science, Volume 95, Issue 2, Page 154-159, February 2004

Blockade of Vascular Endothelial Growth Factor Suppresses Experimental Restenosis After Intraluminal Injury by Inhibiting Recruitment of Monocyte Lineage Cells
Kisho Ohtani 1, Kensuke Egashira 1 (E-mail:
egashira@cardiol.med.kyushu-u.ac.jp), Ken-ichi Hiasa 1, Qingwei Zhao 1, Shiro Kitamoto 1, 2, Minako Ishibashi 1, Makoto Usui 1, Shujiro Inoue 1, Yoshikazu Yonemitsu 2, Katsuo Sueishi 1, Masataka Sata 3, Masabumi Shibuya 4 and Kenji Sunagawa 1
1 Departments of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka
2 Departments of Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka
3 Department of Cardiovascular Medicine, Graduate School of Medical Sciences, University of Tokyo, Tokyo
4 Division of Genetics, Institute of Medical Science, University of Tokyo, Tokyo, Japan
Circulation, Volume 110, Issue 16, Pages 2444-2452, 19 October 2004

Low-voltage electrochemotherapy with low-dose methotrexate enhances survival in mice with osteosarcoma.
Isobe Kenichi 1, Shimizu Tominaga 1, Nikaido Toshio 1 and Takaoka Kunio 1
1 Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan
Clinical Orthopaedics and Related Research, Volume 426, Pages 226-231, September 2004

Navigation of trochlear motor axons along the midbrain-hindbrain boundary by neuropilin 2
Yuji Watanabe 1, 2 (E-mail:
yuji@idac.tohoku.ac.jp), Reiko Toyoda 2 and Harukazu Nakamura 1, 2
1 Department of Molecular Neurobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai 980-8575, Japan
2 Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 980-8575, Japan
Development, Volume 131, Issue 3, Pages 681-692, February 2004

Misrouting of mitral cell progenitors in the Pax6/small eyerat telencephalon
Tadashi Nomura and Noriko Osumi
Division of Developmental Neuroscience, Tohoku University Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan
Development, Volume 131, Issue 4, Pages 787-796, February 2004

Distinct roles of Rac1/Cdc42 and Rho/Rock for axon outgrowth and nucleokinesis of precerebellar neurons toward netrin 1
Frederic Causeret 1, Matias Hidalgo-Sanchez 1, Philippe Fort 2, Stephanie Backer 1, Michel-Robert Popoff 3, Cecile Gauthier-Rouviere 2 and Evelyne Bloch-Gallego 1 (E-mail:
bloch-gallego@cochin.inserm.fr)
1 Institut Cochin, GDPM, INSERM U567, CNRS 8104, Universite Paris V, CHU Cochin, 24 rue du Faubourg Saint Jacques, 75014 Paris, France
2 CRBM/CNRS FRE2593, 1919 Route de Mende, 34293 Montpellier Cedex, France
3 Institut Pasteur, Unite des Bacteries Anaerobies et Toxines, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
Development, Volume 131, Issue 12, Pages 2841-2852, June 2004

The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway
Tatsuya Sato 1, 2, * and Harukazu Nakamura 1, 2 (E-mail:
nakamura@idac.tohoku.ac.jp)
1 Department of Molecular Neurobiology, Graduate School of Life Sciences, Tohoku University, Seiryo-machi 4-1, Aoba-ku, Sendai 980-8575, Japan
2 Institute of Development, Aging and Cancer, Tohoku University, Seiryo-machi 4-1, Aoba-ku, Sendai 980-8575, Japan
* Present address: Skirball Institute of Biomolecular Medicine, New York University School of Medicine, 540 First Avenue, New York, NY 10016, USA
Development, Volume 131, Issue 17, Pages 4275-4285, September 2004

Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation
Jun Hatakeyama 1, Yasumasa Bessho 1, *, Kazuo Katoh 2, Shigeo Ookawara 2, Makio Fujioka 3, Francois Guillemo 4 and Ryoichiro Kageyama 1 (E-mail:
rkageyam@virus.kyoto-u.ac.jp)
1 Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan
2 Department of Anatomy, Jichi Medical School, Tochigi 329-0498, Japan
3 Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan
4 National Institute for Medical Research, Mill Hill, London, NW7 1AA, UK
* Present address: Nara Institute of Science and Technology, Ikoma 630-0101, Japan
Development, Volume 131, Issue 22, Pages 5539-5550, November 2004

Embryonic signaling centers expressing BMP, WNT and FGF proteins interact to pattern the cerebral cortex
Tomomi Shimogori 1, Victoria Banuchi 1, Hanyann Y. Ng 1, Jonathan B. Strauss 1 and Elizabeth A. Grove 1 (E-mail:
egrove@drugs.bsd.uchicago.edu)
1 Department of Neurobiology, Pharmacology and Physiology, Committees on Neurobiology and Developmental Biology, University of Chicago, 947 E 58th Street, MC0926, Chicago, IL 60637, USA
Development, Volume 131, Issue 22, Pages 5639-5647, November 2004

Multiple roles of Sox2, an HMG-box transcription factor in avian neural crest development
Yoshio Wakamatsu 1, 2, Yukinori Endo 3, Noriko Osumi 3 and James A. Weston 4
1 Department of Developmental Neurobiology, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan
2 PRESTO, Japan Science and Technology Corporation, Japan
3 Japan Center for Translational and Advanced Animal Research on Human Diseases, Division of Developmental Neuroscience, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan
4 Institute of Neuroscience, University of Oregon, Eugene, Oregon
Developmental Dynamics, Volume 229, Issue 1, Pages 74-86, January 2004

A primer on using in ovo electroporation to analyze gene function
Catherine E. Krull 1, * (E-mail:
krullc@missouri.edu)
1 Biological Sciences, 108 Lefevre, University of Missouri-Columbia, Columbia, MO 65211
Developmental Dynamics, Volume 229, Issue 3, Pages 433-439, March 2004

Identification of a nonchordate-type classic cadherin in vertebrates: Chicken Hz-cadherin is expressed in horizontal cells of the neural retina and contains a nonchordate-specific domain complex
Koji Tanabe 1, 2, Masatoshi Takeichi 1, 2 and Shinichi Nakagawa 1
1 RIKEN Center for Developmental Biology, Kobe, Japan
2 Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University, Kitashirakawa, Sakyo-ku, Kyoto, Japan
Developmental Dynamics, Volume 229, Issue 4, Pages 899-906, April 2004

piggyBac-mediated somatic transformation of the two-spotted cricket, Gryllus bimaculatus
Yohei Shinmyo 1, Taro Mito 1, Takashi Matsushita 1, Isao Sarashina 1, Katsuyuki Miyawaki 1, Hideyo Ohuchi 1 and Sumihare Noji 1 (E-mail:
noji@bio.tokushima-u.ac.jp)
1 Department of Biological Science and Technology, Faculty of Engineering, The University of Tokushima, 2-1 Minami-Jyosanjima-cho, Tokushima City 770-8506, Japan
Development Growth & Differentiation, Volume 46, Issue 4, Pages 343-349, August 2004

Gene Therapy for Central Diabetes Insipidus: Effective Antidiuresis by Muscle-Targeted Gene Transfer
Masanori Yoshida 1, Yasumasa Iwasaki 2 (E-mail:
iwasakiy@med.nagoya-u.ac.jp), Masato Asai 1, Takeshi Nigawara 2 and Yutaka Oiso 1
1 Departments of Medicine, Nagoya University Graduate School of Medicine and Hospital, Nagoya 466-8550, Japan
2 Department of Clinical Pathophysiology, Nagoya University Graduate School of Medicine and Hospital, Nagoya 466-8550, Japan
Endocrinology, Volume 145, Number 1, Pages 261-268, January 2004

Epidermis-Targeted Gene Transfer Using In Vivo Electroporation
Hiroki Maruyama 1, Jun-Ichi Miyazaki and Fumitake Gejyo
1 Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Epidermal Cells Methods and Protocols, Series: Methods in Molecular Biology, Volume 289, Pages 431-436, October 2004

Transient expression analysis of the mouse ornithine decarboxylase antizyme haploid-specific promoter using in vivo electroporation
Akiko Ike 1, Hiroshi Ohta 1, *, Masayoshi Onishi 1, Naoko Iguchi 1, Yoshitake Nishimune 1 and Masami Nozaki 1 (E-mail:
mnozaki@biken.osaka-u.ac.jp)
1 Department of Science for Laboratory Animal Experimentation, Research Institute for Microbial Diseases, Osaka University, 3-1, Yamadaoka, Suita, Osaka 565-0871, Japan
* Present address: Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN Kobe Institute, 2-2-3 Minatojima-Minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan.
FEBS Letters, Volume 559, Issues 1-3, Pages 159-164, 13 February 2004

Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2
Toshihiko Toyofuku 1, 2, 3, 5, Hong Zhang 1, 2, 5, Atsushi Kumanogoh 2, 3, Noriko Takegahara 2, Fumikazu Suto 4, Junko Kamei 1, 2, Kazuhiro Aoki 1, Masanori Yabuki 1, 2, Masatsugu Hori 1, Hajime Fujisawa 4 and Hitoshi Kikutani 2, 3, 6
1 Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan
2 Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan
3 Core Research For Evolutional Science and Technology (CREST), Japan Science and Technology Corporation, Japan
4 Division of Biological Science, Nagoya University Graduate School of Science, Chikusa-ku, Nagoya 464-8602, Japan
Genes & Development, Volume 18, Issue 4, Pages 435-447, 15 February 2004

Electroporation-mediated muscarinic M3 receptor gene transfer into rat urinary bladder
Masayuki Otani 1, Masaki Yoshida 1, Hitoshi Iwashita 1, Yoshiaki Kawano 1, Kouichi Miyamae 1, Akito Inadome 1, Toru Nishi 2 and Shoichi Ueda 1
1 Departments of Urology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan
2 Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan
International Journal of Urology, Volume 11, Issue 11, Page 1001-1008, November 2004

Application of RNA interference to chicken embryos using small interfering RNA
Fuminori Sato 1, Tetsuto Nakagawa 2, Makoto Ito 2, Yasuo Kitagawa 3, Masa-aki Hattori 1 (E-mail:
mhattori@agr.kyushu-u.ac.jp)
1 Laboratory of Reproductive Physiology and Biotechnology, Department of Animal and Marine Bioresource Sciences
2 Laboratory of Marine Biochemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University, Fukuoka 812-8581, Japan
3 Graduate Program for Regulation of Biological Signals, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan
Journal of Experimental Zoology Part A: Comparative Experimental Biology, Volume 301A, Issue 10, Pages 820-827, 1 October 2004

Green fluorescent protein gene-transfected peafowl somatic cells participate in the development of chicken embryos
Yongmei Xi 1, 2, Yoich Nada 2, Tomoki Soh 1, Noboru Fujihara 1 and Masa-aki Hattori 1 (E-mail:
mhattori@agr.kyushu-u.ac.jp)
1 Laboratory of Reproductive Physiology and Biotechnology, Department of Animal and Marine Bioresource Sciences, Graduate School Kyushu University, Fukuoka 812-8581, Japan
2 Department of Agricultural Ecology, Faculty of Agriculture, Graduate School Kyushu University, Fukuoka 812-8581, Japan
Journal of Experimental Zoology Part A: Comparative Experimental Biology, Volume 301A, Issue 2, Pages 139-149, February 2004

Overexpression of genes in Purkinje cells in the embryonic chicken cerebellum by in vivo electroporation
Jiankai Luo 1 (E-mail:
tluo@mti.uni-jena.de) and Christoph Redies 1
1 Institute of Anatomy I, Friedrich Schiller University, Teichgraben 7, D-07743, Jena, Germany
Journal of Neuroscience Methods, Volume 139, Issue 2, Pages 241-245, 30 October 2004

Local Actions of Endogenous Angiotensin II in Injured Glomeruli
Ji Ma 1, 2, 3 (E-mail:
ji.ma@vanderbilt.edu), Taiji Matsusaka 1, 2, Haichun Yang 2, Hiroshi Kawachi 4, Fujio Shimizu 4, Yoshitaka Isaka 5, Enyu Imai 5, Valentina Kon 3 and Iekuni Ichikawa 1, 3
1 Department of Pediatrics, Tokai University School of Medicine, Isehara, Japan
2 Division of Nephrology, Hua Shan Hospital, Fudan University, Shanghai, China
3 Division of Pediatric Nephrology, Vanderbilt University Medical Center, Nashville, Tennessee
4 Department of Cell Biology, Institute of Nephrology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
5 Division of Nephrology, Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan.
Journal of the American Society of Nephrology, Volume 15, Issue 5, Pages 1268-1276, May 2004

Skeletal muscle targeting in vivo electroporation-mediated HGF gene therapy of bleomycin-induced pulmonary fibrosis in mice
Yukio Umeda 1 (E-mail:
umeda@cc.gifu-u.ac.jp), Tsutomu Marui 1, Yukihiro Matsuno 1, Koyo Shirahashi 1, Hisashi Iwata 1, Hisato Takagi 1, Kunio Matsumoto 2, Toshikazu Nakamura 2, Atsushi Kosugi 3, Yoshio Mori 1 and Hirofumi Takemura 1
1 Advanced Surgery, Department of Organ Pathobiology, Gifu University School of Medicine, Gifu, Japan
2 Molecular Regenerative Medicine, Course of Advanced Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
3 School of Allied Health Sciences, Faculty of Medicine, Osaka University, Suita, Osaka, Japan
Laboratory Investigation, Volume 84, Issue 7, Pages 836-844, July 2004

Gain- and loss-of-function in chick embryos by electroporation
Harukazu Nakamura 1 (E-mil:
nakamura@idac.tohoku.ac.jp), Tatsuya Katahira 1, Tatsuya Sato 1, Yuji Watanabe 1 and Jun-ichi Funahashi 1
1 Department of Molecular Neurobiology, Graduate School of Life Sciences, and Institute of Development, Aging & Cancer, Tohoku University, Seiryo-machi 4-1, Aoba-ku, Sendai 980-8575, Japan
Mechanisms of Development, Volume 121, Issue 9, Pages 1137-1143, September 2004

Cadherins guide migrating Purkinje cells to specific parasagittal domains during cerebellar development
Jiankai Luo 1, 2 (E-mail:
tluo@mit.uni-jena.de), Ullrich Treubert-Zimmermann 1, 2 and Christoph Redies 1, 2
1 Institute of Anatomy, University of Essen School of Medicine, D-45122, Essen, Germany
2 Institute of Anatomy I, University of Jena, D-07740, Jena, Germany
MCN (Molecular and Cellular Neuroscience), Volume 25, Issue 1, Pages 138-152, January 2004

Muscle-targeted interleukin-12 gene therapy of orthotopic hepatocellular carcinoma in mice using in vivo electrosonoporation
Yo-ichi Yamashita 1, Mitsuo Shimada 1, Ryosuke Minagawa 2, Eiji Tsujita 1, Norifumi Harimoto 1, Shinji Tanaka 1, Ken Shirabe 1, Jun-ichi Miyazaki 3 and Yoshihiko Maehara 1
1 Department of Surgery and Science, Graduate School of Medical Sciences
2 Department of Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
3 Division of Stem Cell Regulation Research, Osaka University Graduate School of Medicine, Osaka, Japan
Molecular Cancer Therapeutics, Volume 3, Issue 9, Pages 1177-1182, September 2004

A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons
Minh Dang Nguyen 1, 2 (E-mail:
minh-dang_nguyen@hms.harvard.edu), Tianzhi Shu 1, Kamon Sanada 1, Roxanne C. Lariviere 2, *, Huang-Chun Tseng 1, Sang Ki Park 1, Jean-Pierre Julien 2, * and Li-Huei Tsai 1 (E-mail: li-huei_tsai@hms.harvard.edu)
1 Department of Pathology, Harvard Medical School and Howard Hughes Medical Institute, 77 Avenue Louis Pasteur, New Research Building, Room 856-8, MA 02115, USA
2 Centre for Research in Neuroscience, The Montreal General Hospital Research Institute, 1650 Cedar Avenue, Montreal, Quebec, H3G 1A4, Canada
* Present address: CHUL Research Center, Department of Anatomy and Physiology, Laval University, 2705 Boulevard Laurier, Sainte-Foy, Quebec, G1V 4G2, Canada
Nature Cell Biology, Volume 6, Number 7, Pages 595-608, July 2004

RGM and its receptor neogenin regulate neuronal survival.
Eiji Matsunaga 1, Servane Tauszig-Delamasure 2, Philippe P. Monnier 3, 4, Bernhard K. Mueller 3, 5, Stephen M. Strittmatter 6, Patrick Mehlen 2 and Alain Chedotal 1, 7
1 UMR CNRS 7102, Universite Paris 6, 9 Quai Saint Bernard, 75005 Paris, France
2 CNRS UMR 5534, Label 'la Ligue', University of Lyon, 69622 Villeurbanne, France
3 MigraGen AG, Spemannstrasse 34, D-72076 Tuebingen, Germany
4 Toronto Western Hospital, 399 Bathurst Street, Toronto, M5T258, ON, Canada
5 Abboto GmbH & Co KG, Knollstrasse, 67601 Ludwigshafen, Germany
6 Department of Neurology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA
Nature Cell Biology, Volume 6, Issue 8, Pages 749-755, August 2004

Guidance of myocardial patterning in cardiac development by Sema6D reverse signalling
Toshihiko Toyofuku 1, 2, 3, Hong Zhang 1, 2, Atsushi Kumanogoh 2, 3, Noriko Takegahara 2, Masanori Yabuki 1, 2, Koichiro Harada 1, 2, Masatsugu Hori 1 and Hitoshi Kikutani 2, 3
1 Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan
2 Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan
3 CREST, Japan Science and Technology Corporation, Japan
Nature Cell Biology, Volume 6, Number 12, Pages 1204-1211, December 2004

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling.
Xi C He 1, *, Jiwang Zhang 1, *, Wei-Gang Tong 1, Ossama Tawfik 2, Jason Ross 1, David H Scoville 1, 2, Qiang Tian 3, Xin Zeng 4, Xi He 4, Leanne M Wiedemann 1, 2, Yuji Mishina 5 and Linheng Li 1, 2 (E-mail:
lil@stowers-institute.org)
1 Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, Missouri 64110, USA
2 Department of Pathology and Laboratory Medicine, Kansas University Medical Center, Kansas City, Kansas 66160, USA
3 Institute of Systemsbiology, Seattle, Washington 98103, USA
4 Children's Hospital and Harvard University Medical School, Boston, Massachusetts 02115, USA
5 Laboratory of Reproductive and Developmental Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
* These two authors contributed equally to this work.
Nature Genetics, Volume 36, Number 10, Pages 1117-1121, October 2004

Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling
Makoto Inoue 1, Md Harunor Rashid 1, Ryousuke Fujita 1, James J A Contos 2, Jerold Chun 3 and Hiroshi Ueda 1
1 Division of Molecular Pharmacology and Neuroscience, Nagasaki University, Graduate School of Biomedical Sciences, 1-14 Bunkyo-machi, Nagasaki, 852-8521, Japan
2 Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N., Seattle, Washington 98109-1024, USA
3 Department of Molecular Biology, Helen L. Dorris Institute for Neurological and Psychiatric Disorders, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, USA
Nature Medicine, Volume 10, Number 7, Pages 712-718, July 2004

Direct transfer of hepatocyte growth factor gene into kidney suppresses cyclosporin A nephrotoxicity in rats
Koji Yazawa 1, Yoshitaka Isaka 2, Shiro Takahara 1, Enyu Imai 2, Naotsugu Ichimaru 1, Yi Shi 1, Yukiomi Namba 1 and Akihiko Okuyama 1
1 Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan
2 Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
Nephrology Dialysis Transplantation, Volume 19, Issue 4, Pages 812-816, April 2004

A role for ligand-gated ion channels in rod photoreceptor development
Tracy L. Young and Constance L. Cepko
Department of Genetics, Howard Hughes Medical Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
Neuron, Volume 41, Issue 6, Pages 867-879, 25 March 2004

Disabled-1-Regulated Adhesion of Migrating Neurons to Radial Glial Fiber Contributes to Neuronal Positioning during Early Corticogenesis
Kamon Sanada 1, Amitabh Gupta 1 and Li-Huei Tsai 1, 2 (E-mail:
li-huei_tsai@hms.harvard.edu)
1 Department of Pathology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115 USA
2 Howard Hughes Medical Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115 USA
Neuron, Volume 42, Issue 2, Pages 197-211, 22 April 2004

Electroporation-mediated gene transfer system applied to cultured CNS neurons
Izumi Kawabata 1, Tatsuya Umeda 1, Kazuhiro Yamamoto 2 and Shigeo Okabe 1, 2, 3 (E-mail:
okabe.cbio@tmd.ac.jp)
1 Department of Anatomy and Cell Biology, School of Medicine, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8519
2 Moleculer Neurophysiology Group, Neuroscience Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, 305-8566
3 Core Research for Evolution Science and Technology (CREST), Japan Science and Technology Corporation (JST), Kawaguchi, 332-0012, Japan
Neuroreport, Volume 15, Issue 6, Pages 971-975, 29 April 2004

Electroporation and RNA interference in the rodent retina in vivo and in vitro *
Protocol for in vivo electroporation into mouse/rat retina
Takahiko Matsuda (E-mail:
tmatsuda@genetics.med.harvard.edu) and Constance L. Cepko (E-mail: cepko@genetics.med.harvard.edu)
Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115
* PNAS (Proceedings of the National Academy of Sciences of the United States of America), Volume 101, Number 1, Pages 16-22, 6 January 2004

Sequence-specific gene silencing in murine muscle induced by electroporation-mediated transfer of short interfering RNA
Tsunao Kishida 1, Hidetsugu Asada 1, Satoshi Gojo 3, Suzuyo Ohashi 2, Masaharu Shin-Ya 1, Kakei Yasutomi 1, Ryu Terauchi 2, Kenji A. Takahashi 2, Toshikazu Kubo 2, Jiro Imanishi 1, Osam Mazda 1
1 Department of Microbiology, Kyoto Prefectural University of Medicine, Kyoto 602- 8566, Japan
2 Department of Orthopaedic Surgery, Kyoto Prefectural University of Medicine, Kyoto 602- 8566, Japan
3 Department of Cardiovascular Surgery, Saitama Medical Center, Kawagoe, Saitama 350- 8550, Japan
The Journal of Gene Medicine, Volume 6, Issue 1, Pages 105-110, January 2004

Post-secretion neutralization of transgene-derived effect: soluble erythropoietin receptor/IgG1Fc expressed in liver neutralizes erythropoietin produced in muscle
H. Maruyama 1 (E-mail
hirokim@med.niigata-u.ac.jp), M. Higuchi 2, N. Higuchi 1, S. Kameda 1, M. Saito 2, M. Sugawa 2, J. Matsuzaki 2, T. Neichi 2, S. Yokoyama 2, Y. Miyazaki 3, J. Miyazaki 4 and F. Gejyo 1
1 Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachidori, Niigata 951-8120, Japan
2 Chugai Pharmaceutical Co., Ltd., 2-1-9 Kyobashi, Chuou-ku, Tokyo 104-8301, Japan
3 Department of Hematology, Molecular Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University School of Medicine, 1-12-4 Sakamoto, Nagasaki 853-8523, Japan
4 Division of Stem Cell Regulation Research, G6, Osaka University Medical School, 2-2 Yamadaoka, Suita 565-0871, Japan
The Journal of Gene Medicine, Volume 6, Issue 2, Pages 228-237, February 2004

Generation of Reelin-Positive Marginal Zone Cells from the Caudomedial Wall of Telencephalic Vesicles
Keiko Takiguchi-Hayashi 1, Mariko Sekiguchi 1, Shizuko Ashigaki 1, 3, Masako Takamatsu 3, Hiroshi Hasegawa 3, Rika Suzuki-Migishima 2, Minesuke Yokoyama 2 , Shigetada Nakanishi 4, 5 and Yasuto Tanabe 1, 3
1 Translational Research Department, Molecular Bio-Medicine Unit, Japan Science and Technology, Mitsubishi Kagaku Institute of Life Sciences, Machida, Tokyo, 194-8511
2 Mouse Genome Technology Center, Japan Science and Technology, Mitsubishi Kagaku Institute of Life Sciences, Machida, Tokyo, 194-8511
3 Precursory Research for Embryonic Science and Technology, Japan Science and Technology, Mitsubishi Kagaku Institute of Life Sciences, Machida, Tokyo, 194-8511
4 Department of Biological Sciences, Faculty of Medicine, Kyoto University, Kyoto 606-8501, Japan
5 Department of Molecular and System Biology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan
The Journal of Neuroscience, Volume 24, Issue 9, Pages 2286-2295, 3 March 2004

Laminar Patterning in the Developing Neocortex by Temporally Coordinated Fibroblast Growth Factor Signaling
Hiroshi Hasegawa 1, Shizuko Ashigaki 1, Masako Takamatsu 1, Rika Suzuki-Migishima 2, Norihiko Ohbayashi 3, Nobuyuki Itoh 4, Shinji Takada 3 and Yasuto Tanabe 1 (E-mail:
stakada@nibb.ac.jp)
1 Neural Organization Research Team, Mitsubishi Kagaku Institute of Life Sciences, Precursory Research for Embryonic Science and Technology, Japan Science and Technology, Machida, Tokyo 194-8511, Japan
2 Mouse Genome Technology Center, Mitsubishi Kagaku Institute of Life Sciences, Precursory Research for Embryonic Science and Technology, Japan Science and Technology, Machida, Tokyo 194-8511, Japan
3 Center for Integrative Bioscience, Okazaki National Research Institutes, Myodaiji-cho, Okazaki 444-8585, Japan
4 Department of Genetic Biochemistry, Kyoto University Graduate School of Pharmaceutical Sciences, Yoshida-Shimoadachi, Sakyo, Kyoto 606-8501, Japan
The Journal of Neuroscience, Volume 24, Issue 40, Pages 8711-8719, 6 October 2004

Filamin A and FILIP (Filamin A-Interacting Protein) Regulate Cell Polarity and Motility in Neocortical Subventricular and Intermediate Zones during Radial Migration
Takashi Nagano 1, Soichi Morikubo 1, 2 and Makoto Sato 1, 3 (E-mail:
makosato@fmsrsa.fukui-med.ac.jp)
1 Division of Cell Biology and Neuroscience, Department of Morphological and Physiological Sciences, University of Fukui, Matsuoka, Fukui 910-1193, Japan
2 Division of Ophthalmology, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences, University of Fukui, Matsuoka, Fukui 910-1193, Japan
3 Solution Oriented Research for Science and Technology, Japan Science and Technology Corporation, Kawaguchi, Saitama 332-0012, Japan
The Journal of Neuroscience, Volume 24, Issue 43, Pages 9648-9657, 27 October 2004

Suppression of cyclosporine a nephrotoxicity in vivo by transforming growth factor beta receptor-immunoglobulin G chimeric protein
Xin Jing 1, Homma Toshio 1, Matsusaka Taiji 1, Ma Ji 1, Isaka Yoshitaka 1, Imai Enyu 1, Ichikawa Iekuni 1
1 Department of Pediatrics, Tokai University School of Medicine, Isehara, Kanagawa, Japan
Transplantation, Volume 77, Number 9, Pages 1433-1442, 15 May 2004



[2003]
Dramatic Expansion of Germinal Stem Cells by Ectopically Expressed Human Glial Cell Line-Derived Neurotrophic Factor in Mouse Sertoli Cells
Kentaro Yomogida 1, Yo Yagura 1, Yuko Tadokoro 1 and Yoshitake Nishimune 1
1 Department of Science for Laboratory Animal Experimentation, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka,suita, Osaka 565-0871, Japan
Biology of Reproduction, Volume 69, Issue 4, Pages 1303-1307, October 2003

Bleomycin-mediated electrochemotherapy in mouse NR-S1 carcinoma
Akira Kitamura 1 (E-mail:
a-kit@net.nagasaki-u.ac.jp)
1 Second Department of Oral and Maxillofacial Surgery, Nagasaki University School of Dentistry, 1-7-1 Sakamoto, 852-8588, Nagasaki, Japan
Cancer Chemotherapy and Pharmacology, Volume 51, Number 4, Pages 359-362, April 2003

Serine 732 Phosphorylation of FAK by Cdk5 Is Important for Microtubule Organization, Nuclear Movement, and Neuronal Migration
Zhigang Xie 1, Kamon Sanada 1, Benjamin Adam Samuels 1, 2, Heather Shih 1 and Li-Huei Tsai 1, 2, 3 (E-mail:
li-huei_tsai@hms.harvard.edu)
1 Department of Pathology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115 USA
2 Program in Neuroscience, Harvard University, 200 Longwood Avenue, Boston, MA 02115 USA
3 Howard Hughes Medical Institute, 200 Longwood Avenue, Boston, MA 02115 USA
Cell, Volume 114, Issue 4, Pages 469-482, 22 August 2003

Negative Feedback Regulation of FGF Signaling Levels by Pyst1/MKP3 in Chick Embryos
Maxwell C. Eblaghie 1, 4, J. Simon Lunn 1, 2, 4, Robin J. Dickinson 3, Andrea E. Munsterberg 1, 5, Juan-Jose Sanz-Ezquerro 1, Elizabeth R. Farrell 1, Joanne Mathers 3, Stephen M. Keyse 3 (E-mail:
stephen.keyse@cancer.org.uk), Kate Storey 1, 2 (E-mail: k.g.storey@dundee.ac.uk) and Cheryll Tickle 1 (E-mail: c.a.tickle@dundee.ac.uk)
1 Division of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, United Kingdom
2 Neural Development Group, Division of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, United Kingdom
3 Cancer Research UK, Molecular Pharmacology Unit, Biomedical Research Centre, Level 5, Ninewells Hospital, Dundee DD1 9SY, United Kingdom
Current Biology, Volume 13, Issue 12, Pages 1009-1018, 17 June 2003

The role of Grg4 in tectal laminar formation
Sayaka Sugiyama 1 and Harukazu Nakamura 2 (E-mail:
nakamura@idac.tohoku.ac.jp)
1 Laboratory for Neuronal Circuit Development, Brain Science Institute, RIKEN, 351-0198 Japan
2 Department of Molecular Neurobiology, Institute of Development, Aging and Cancer, and Graduate School of Life Sciences, Tohoku University, Seiryo-machi 4-1, Aoba-ku, Sendai 980-8575, Japan
Development, Volume 130, Issue 3, Pages 451-462, February 2003

Irx4-mediated regulation of Slit1 expression contributes to the definition of early axonal paths inside the retina
Zhe Jin 1, Jinhua Zhang 1, Avihu Klar 2, Alain Chedotal 3, Yi Rao 4, Constance L. Cepko 5 and Zheng-Zheng Bao 1 (E-mail:
zheng.bao@umassmed.edu)
1 Department of Medicine, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
2 Department of Anatomy and Cell Biology, The Hebrew University-Hadassah Medical School, PO Box 12272, Jerusalem 91120, Israel
3 Institut de la Sante et de le Recherche Medicale U106, Batiment de Pediatrie, Hopital de la Salpetriere, 47 Boulevard de I'Hopital, 75013, Paris, France
4 Department of Anatomy and Neurobiology, Washington University School of Medicine, Box 8108, 660 S. Euclid Avenue, St Louis, MO 63110, USA
5 Department of Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
Development, Volume 130, Issue 6, Pages 1037-1048, March 2003

Tbx4-Fgf10 system controls lung bud formation during chicken embryonic development
Jun-ichi Sakiyama 1, Atsushi Yamagishi 1, 2 and Atsushi Kuroiwa 1 (E-mail:
i45240a@nucc.cc.nagoya-u.ac.jp)
1 Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8602 Japan
2 CREST, Japan Science and Technology Corporation (JST), Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8602 Japan
Development, Volume 130, Issue 7, Pages 1225-1234, April 2003

Nodal signaling induces the midline barrier by activating Nodal expression in the lateral plate
Masamichi Yamamoto 1, Naoki Mine 1, Kyoko Mochida 1, Yasuo Sakai 1, *, Yukio Saijoh 1, Chikara Meno 1 and Hiroshi Hamada 1 (E-mail:
hamada@fbs.osaka-u.ac.jp)
1 Developmental Genetics Group, Graduate School of Frontier Biosciences, Osaka University, and CREST, Japan Science and Technology Corporation (JST), 1-3 Yamada-oka, Suita, Osaka 565-0871, Japan
* Present address: E. Kennedy Shriver Center, Division of Developmental Neuroscience, 200 Trapelo Rd, Waltham, MA 02254, USA
Development, Volume 130, Issue 9, Pages 1795-1804, May 2003

Tbx5 and Tbx4 trigger limb initiation through activation of the Wnt/Fgf signaling cascade
Jun K. Takeuchi 1, *, Kazuko Koshiba-Takeuchi 1, *, Takayuki Suzuki 1, Mika Kamimura 1, Keiko Ogura 1 and Toshihiko Ogura 1 (E-mail:
ogura@bs.aist-nara.ac.jp)
1 Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5, Takayama, Ikoma, Nara 630-0101, Japan
* Present address: Cardiovascular Research, The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada
Development, Volume 130, Issue 12, Pages 2729-2739, June 2003

Tbx5 specifies the left/right ventricles and ventricular septum position during cardiogenesis
Jun K. Takeuchi 1, Makoto Ohgi 1, Kazuko Koshiba-Takeuchi 1, Hidetaka Shiratori 2, Ichiro Sakaki 1, Keiko Ogura 3, Yukio Saijoh 2 and Toshihiko Ogura 3
1 Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5, Takayama, Ikoma, Nara 630-0101, Japan
2 Division of Molecular Biology, Institute for Molecular and Cellular Biology, Osaka University, and Core Research for Evolutional Science and Technology Corporation, Osaka 565-0871, Japan
3 Department of Developmental Neurobiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai 980-8575, Japan
Development, Volume 130, Issue 24, Pages 5953-5964, December 2003

Functional Analysis of Chicken Sox2 Enhancers Highlights an Array of Diverse Regulatory Elements that Are Conserved in Mammals
Masanori Uchikawa 1, Yoshiko Ishida 1, Tatsuya Takemoto 1, Yusuke Kamachi 1 and Hisato Kondoh 1 (E-mail:
kondohh@fbs.osaka-u.ac.jp)
1 Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan
Developmental Cell, Volume 4, Number 4, Pages 509-519, April 2003

Analysis of transcription regulatory regions of embryonic chicken pepsinogen (ECPg) gene
Kumiko Watanuki 1 (E-mail:
kumikumi@comp.metro-u.ac.jp) and Sadao Yasugi 1
1 Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, Hachioji, Tokyo, Japan
Developmental Dynamics, Volume 228, Issue 1, Pages 51-58, September 2003

Deltex/Dtx mediates NOTCH signaling in regulation of Bmp4 expression in cranial neural crest formation during avian development
Yukinori Endo 1, Noriko Osumi 1, 2 and Yoshio Wakamatsu 2, 3 (Email:
wakasama@mail.cc.tohoku.ac.jp)
1 Center for Translational and Advanced Animal Research on Human Diseases, Division of Developmental Neuroscience
2 Department of Developmental Neurobiology, Graduate School of Medicine, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575
3 Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Corporation, 4-1-8 Hon-machi, Kawaguchi, Saitama 332-0012, Japan
Development, Growth & Differentiation, Volume 45, Issue 3, Pages 241-248, June 2003

Gene silencing in chick embryos with a vector-based small interfering RNA system.
Tatsuya Katahira 1 and Harukazu Nakamura 1, 2 (Email:
nakamura@idac.tohoku.ac.jp)
1 Laboratory of Molecular Neurobiology, Institute of Development, Aging and Cancer (IDAC)
2 Graduate School of Life Sciences, Tohoku University, Seiryo-machi 4-1, Aoba-ku, Sendai 980-8575, Japan
Development Growth & Differentiation, Volume 45, Issue 4, Pages 361-367, August 2003

Axonal morphogenesis controlled by antagonistic roles of two CRMP subtypes in microtubule organization
Junichi Yuasa-Kawada 1, Ryoko Suzuki 1, Fumi Kano 2, Takeshi Ohkawara 1, Masayuki Murata 2 and Masaharu Noda 1 (E-mail:
madon@nibb.ac.jp)
1 Division of Molecular Neurobiology, National Institute for Basic Biology, and Department of Molecular Biomechanics, The Graduate University for Advanced Studies, Okazaki, 444 8585, Japan
2 Department of Molecular Physiology, National Institute for Physiological Sciences, Okazaki, Japan
European Journal of Neuroscience, Volume 17, Issue 11, Pages 2329-2343, June 2003

IGF-I gene transfer by electroporation promotes regeneration in a muscle injury model
T Takahashi 1, K Ishida 1, K Itoh 1, Y Konishi 2, K-I Yagyu 2, A Tominaga 2, 3, J-I Miyazaki 4 and H Yamamoto 1
1 Department of Orthopaedic Surgery, Kochi Medical School, Nankoku, Kochi, Japan
2 Medical Research Center, Kochi Medical School, Nankoku, Kochi, Japan
3 Department of Medical Biology, Kochi Medical School, Nankoku, Kochi, Japan
4 Department of Molecular Therapy, Division of Stem Cell Regulation Research, Osaka University Medical School, Suita, Osaka, Japan
Gene Therapy, Volume 10, Number 8, Pages 612-620, April 2003

Hepatocyte growth factor gene therapy accelerates regeneration in cirrhotic mouse livers after hepatectomy
F Xue 1, T Takahara 1, Y Yata 1, Y Kuwabara 1, E Shinno 1, K Nonome 1, M Minemura 1, S Takahara 2, X Li 3, E Yamato 4 and A Watanabe 1
1 Third Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan
2 Department of Urology, Osaka University Medical School, Osaka, Japan
3 Laboratory of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan
4 Department of Nutrition and Physiological Chemistry, Osaka University Medical School, Osaka, Japan
Gut, Volume 52, Number 5, Pages 694-700, May 2003

Ectopic Bone Formation by Human Bone Morphogenetic Protein-2 Gene Transfer to Skeletal Muscle Using Transcutaneous Electroporation
Mariko Kawai 1, Kazuhisa Bessho 1, Shinji Kaihara 1, Junya Sonobe 1, Kimimitsu Oda 1, Tadahiko Iizuka 2, Hiroki Maruyama 3
1 Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan
2 Department of Biochemistry, Niigata University School of Dentistry, Niigata 951-8514, Japan
3 Division of Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8120, Japan
Human Gene Therapy, Volume 14, Number 16, Pages 1547-1556, November 2003

Effect of CaCl2 concentration on the rate of foreign gene transfer and expression by in vivo electroporation in the mouse ovary
Takayuki Suzuki 1, Jun Tsunekawa 1, Atsushi Murai 1 and Tatsuo Muramatsu 1
1 Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan
International Journal of Molecular Medicine, Volume 12, Number 3, Pages 365-358, September 2003

Electrochemotherapy for digital chondrosarcoma
Tominaga Shimizu 1, Toshio Nikaido 3, Hiroki Gomyo 1, Yasuo Yoshimura 1, Akiko Horiuchi 2, Kenichi Isobe 1, Sohei Ebara 1 and Kunio Takaoka 1
1 Department of Orthopedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan
2 Department of Obstetrics and Gynecology, Shinshu University School of Medicine, Matsumoto, Japan
3 Department of Organ Regeneration, Shinshu University Graduate School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan
Journal of Orthopaedic Science, Volume 8, Number 2, Pages 248-251, March 2003

Efficient gene delivery to articular cartilage using electroporation
Rie Katayama 1 (E-mail:
riek@ms.toyama-mpu.ac.jp), Tomoatsu Kimura 1, Tetsuya Tomita 2, Hiroaki Matsuno 1, Yuji Morita 1, Isao Matsushita 1 and Ryuichi Gejo 1
1 Department of Orthopaedic Surgery, Faculty of Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, 930-0194, Japan
2 Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Japan
Modern Rheumatology, Volume 13, Number 3, Pages 243-249, September 2003

Electrochemo-Gene Therapy of Cancer: Intratumoral Delivery of Interleukin-12 Gene and Bleomycin Synergistically Induced Therapeutic Immunity and Suppressed Subcutaneous and Metastatic Melanomas in Mice
Tsunao Kishida 1, Hidetsugu Asada 1, Yoshiki Itokawa 2, Kakei Yasutomi 1, Masaharu Shin-Ya 1, Satoshi Gojo 3, Feng-De Cui 1, Yuji Ueda 2, Hisakazu Yamagishi 2, Jiro Imanishi 1 and Osam Mazda 1 (E-mail:
mazda@basic.kpu-m.ac.jp)
1 Department of Microbiology, Kyoto Prefectural University of Medicine, Kamikyo, Kyoto 602-8566, Japan
2 Department of Digestive Surgery, Kyoto Prefectural University of Medicine, Kamikyo, Kyoto 602-8566, Japan
3 Department of Cardiovascular Surgery, Saitama Medical Center, Kawagoe, Saitama 350-8550, Japan
Molecular Therapy, Volume 8, Number 5, Pages 738-745, November 2003

Emx2 patterns the neocortex by regulating FGF positional signaling
Tomomi Fukuchi-Shimogori 1 and Elizabeth A Grove 1 (E-mail:
egrove@drugs.bsd.uchicago.edu)
1 Department of Neurobiology, Pharmacology and Physiology, University of Chicago, 947 East 58th Street, MC0926, Chicago, Illinois 60637, USA.
Nature Neuroscience, Volume 6, Number 8, Pages 825-831, August 2003

Layering defect in p35 deficiency is linked to improper neuronal-glial interaction in radial migration
Amitabh Gupta 1, *, Kamon Sanada 1, *, David T Miyamoto 2, Susan Rovelstad 3, Bagirathy Nadarajah 4, Alan L Pearlman 3, Jan Brunstrom 3 and Li-Huei Tsai 1 (E-mail:
li-huei_tsai@hms.harvard.edu)
1 Department of Pathology, Harvard Medical School and Howard Hughes Medical Institute, Boston, Massachusetts 02115, USA
2 Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
3 Departments of Neurology and Cell Biology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
4 Division of Neuroscience, School of Biological Sciences, University of Manchester, Manchester M13 9PT, UK
* These authors contributed equally to this work.
Nature Neuroscience, Volume 6, Number 12, Pages 1284-1291, December 2003

Methylation of CpG dinucleotides in the open reading frame of a testicular germ cell-specific intronless gene, Tact1/Actl7b, represses its expression in somatic cells
Mizue Hisano 1, Hirosi Ohta 1, Yoshitake Nishimune 1 and Masami Nozaki 1 (Email:
mnozaki@biken.osaka-u.ac.jp)
1 Science Animal Experimentation, Research Institute for Microbial Diseases, Osaka University, 3-1, Yamadaoka, Suita, Osaka 565-0871, Japan
Nucleic Acids Research, Volume 31, Number 16, Pages 4797-4804, 15 August 2003

Transgenic planarian lines obtained by electroporation using transposon-derived vectors and an eye-specific GFP marker
C. Gonzalez-Estevez 1, T. Momose 2, W. J. Gehring 3 and E. Salo 1 (E-mail:
esalo@ub.edu)
1 Departament de Genetica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain
2 Department of Zoology, Pharmazentrum, University of Basel, Klingelbergstrasse 50, CH-4056 Basel, Switzerland
3 Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, CH-4056 Basel, Switzerland
PNAS (Proceedings of the National Academy of Sciences of the United States of America), Volume 100, Number 24, Pages 14046-14051, 25 November 2003

Possible involvement of antitumor immunity in the eradication of colon 26 induced by low-voltage electrochemotherapy with bleomycin
Shinichi Miyazaki 1, Yoshio Gunji 1, Hisahiro Matsubara 1, Hideaki Shimada 1, Masaya Uesato 1, Takao Suzuki 1, Teruo Kouzu 2, Takenori Ochiai 1
1 Department of Academic Surgery (M9), Graduate School of Medicine, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan
2 Department of Endoscopic Diagnostics and Therapeutics, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan
Surgery Today, Volume 33, Number 1, Pages 39-44, January 2003

The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration
Takeshi Kawauchi 1, 2, Kaori Chihama 1, 2, Yo-ichi Nabeshima 1 and Mikio Hoshino 1, 2 (E-mail:
mikio@lmls.med.kyoto-u.ac.jp)
1 Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501
2 Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Corporation (JST), Kawaguchi, Saitama 332-0012, Japan
The EMBO Journal, Volume 22, Number 16, Pages 4190-4201, August 2003

Gene transfer into the liver by plasmid injection into the portal vein combined with electroporation
Shogo Kobayashi 1, Keizo Dono 1, Toshiyuki Tanaka 2, Shiro Takahara 2, Yoshitaka Isaka 3, Enyu Imai 3, Hiroaki Nagano 1, Kato Tomoaki 1, Koji Umeshita 1, Shoji Nakamori 1, Masato Sakon 1 and Morito Monden 1 (E-mail:
monden@surg2.med.osaka-u.ac.jp)
1 Department of Surgery and Clinical Oncology, Graduate School of Medicine, Osaka University, Osaka, Japan
2 Department of Urology, Graduate School of Medicine, Osaka University, Osaka, Japan
3 Department of Internal Medicine and Therapeutics, Graduate School of Medicine, Osaka University, Osaka, Japan
The Journal of Gene Medicine, Volume 5, Issue 3, Pages 201-208, March 2003

Electroporation-mediated ex vivo gene transfer into graft not requiring injection pressure in orthotopic liver transplantation
Shogo Kobayashi 1, Keizo Dono 1, Shiro Takahara 2, Yoshitaka Isaka 3, Enyu Imai 3, Lu Zhenhui 1, Hiroaki Nagano 1, Kato Tomoaki 1, Koji Umeshita 1, Shoji Nakamori 1, Masato Sakon 1 and Professor Morito Monden 1
1 Department of Surgery and Clinical Oncology, Graduate School of Medicine, Osaka University, Osaka, Japan
2 Department of Urology, Graduate School of Medicine, Osaka University, Osaka, Japan
3 Department of Internal Medicine and Therapeutics, Graduate School of Medicine, Osaka University, Osaka, Japan
The Journal of Gene Medicine, Volume 5, Issue 6, Pages 510-517, June 2003

Mammalian BarH1 Confers Commissural Neuron Identity on Dorsal Cells in the Spinal Cord
Rie Saba 1, 2, Norio Nakatsuji 2 and Tetsuichiro Saito 2
1 Department of Genetics, The Graduate University for Advanced Studies, National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan
2 Department of Development and Differentiation, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan
The Journal of Neuroscience, Volume 23, Issue 6, Pages 1987-1991, 15 March 2003

Locus-Specific Rescue of GluR1 NMDA Receptors in Mutant Mice Identifies the Brain Regions Important for Morphine Tolerance and Dependence
Makoto Inoue 1, Masayoshi Mishina 2, 3, and Hiroshi Ueda 1
1 Division of Molecular Pharmacology and Neuroscience, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8521, Japan
2 Department of Molecular Neurobiology and Pharmacology, Graduate School of Medicine, University of Tokyo, Tokyo 113-0033, Japan
3 Solution-Oriented Research for Science and Technology, Japan Science and Technology Corporation, Tokyo 113-0033, Japan
The Journal of Neuroscience, Volume 23, Issue 16, Pages 6529-6536, 23 July 2003

Multipolar Migration: The Third Mode of Radial Neuronal Migration in the Developing Cerebral Cortex
Hidenori Tabata 1, 2 and Kazunori Nakajima 1, 2, 3
1 Department of Anatomy, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan
2 Department of Molecular Neurobiology, Institute of DNA Medicine, Jikei University School of Medicine, Minato-ku, Tokyo 105-8461, Japan
3 Precursory Research for Embryonic Science and Technology, Japan Science and Technology Corporation, Kawaguchi, Saitama 332-0012, Japan
The Journal of Neuroscience, Volume 23, Issue 31, Pages 9996-10001, 5 November 2003


[2002]
Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary hypertension in rats
Yasuhiro Ikeda 1, Yoshikazu Yonemitsu 1, Chu Kataoka 2, Shiro Kitamoto 2, Terutoshi Yamaoka 3, Ken-Ichi Nishida 4, Akira Takeshita 2, Kensuke Egashira 2, and Katsuo Sueishi 1
1 Division of Pathophysiological and Experimental Pathology, Department of Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582
2 Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582
3 Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582
4 Tokyo R&D Center, Daiichi Pharmaceutical Company, Tokyo 103-8234, Japan
American Journal of Physiology - Heart and Circulatory Physiology, Volume 283, Issue 5, Pages H2021-H2028, November 2002

In Vivo Gene Transfer of Hepatocyte Growth Factor to Skeletal Muscle Prevents Changes in Rat Kidneys After 5/6 Nephrectomy
Toshiyuki Tanaka 1, Naotsugu Ichimaru 2, Shiro Takahara 2 (E-mail:
takahara@uro.med.osaka-u.ac.jp), Koji Yazawa 2, Motoaki Hatori 1, Kazuhiro Suzuki 1, Yoshitaka Isaka 3, Toshiki Moriyama 3, Enyu Imai 3, Haruhito Azuma 5, Toshikazu Nakamura 4, Akihiko Okuyama 2 and Hidetoshi Yamanaka 1
1 Department of Urology, Gunma University School of Medicine, Maebashi, Gunma, Japan
2 Department of Urology, Biomedical Research Center, Osaka Medical College, Takatsuki, Osaka, Japan
3 Department of Internal Medicine and Therapeutics, Biomedical Research Center, Osaka Medical College, Takatsuki, Osaka, Japan
4 Department of Urology, Biomedical Research Center, Osaka Medical College, Takatsuki, Osaka, Japan
5 Division of Biochemistry, Biomedical Research Center, Osaka University Graduate School of Medicine, Suita-city, Osaka, Japan
American Journal of Transplantation, Volume 2, Issue 9, Pages 828-836, October 2002

Successful genetic transduction in vivo into synovium by means of electroporation
Suzuyo Ohashi 1, Toshikazu Kubo 1, Tsunao Kishida 2, Takumi Ikeda 1, Kenji Takahashi 1, Yuji Arai 1, Ryu Terauchi 1, Hidetsugu Asada 2, Jiro Imanishi 2 and Osam Mazda 2 (E-mail:
mazda@basic.kpu-m.ac.jp)
1 Department of Orthopaedic Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
2 Department of Microbiology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, Kyoto 602-8566, Japan
Biochemical and Biophysical Research Communications, Volume 293, Issue 5, Pages 1530-1535, 24 May 2002

Electroporated Transgene-Rescued Spermatogenesis in Infertile Mutant Mice with a Sertoli Cell Defect
Kentaro Yomogida 1, Yo Yagura 1 and Yoshitake Nishimune 1 (E-mail:
nishimun@biken.osaka-u.ac.jp)
1 Department of Science for Laboratory Animal Experimentation, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan
Biology of Reproduction, Volume 67, Issue 3, Pages 712-717, September 2002

Ectopic bone formation by electroporatic transfer of bone morphogenetic protein-4 gene
K. N. Kishimoto 1, 2 (E-mail:
k-kishi@mail.cc.tohoku.ac.jp), Y. Watanabe 2, H. Nakamura 2 and S. Kokubun 1
1 Department of Orthopaedic Surgery, Tohoku University School of Medicine, Sendai, Japan
2 Department of Molecular Neurobiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan
Bone, Volume 31, Issue 2, Pages 340-347, August 2002

Axonal protein synthesis provides a mechanism for localized regulation at an intermediate target
Perry A. Brittis 1, Qiang Lu 1 and John G. Flanagan 1 (E-mail:
flanagan@hms.harvard.edu)
1 Department of Cell Biology and Program in Neuroscience Harvard Medical School Boston, Massachusetts 02115
Cell, Volume 110, Issue 2, Pages 223-235, 26 July 2002

Vascular Endothelial Growth Factor Is Necessary in the Development of Arteriosclerosis by Recruiting/Activating Monocytes in a Rat Model of Long-Term Inhibition of Nitric Oxide Synthesis
Qingwei Zhao 1, Kensuke Egashira 1 (E-mail:
egashira@cardiol.med.kyushu-u.ac.jp), Shujiro Inoue 1, Makoto Usui 1, Shiro Kitamoto 1, Weihua Ni 1, Minako Ishibashi 1, Ken-ichi Hiasa 1, Toshihiro Ichiki 1, Masabumi Shibuya 2, Akira Takeshita 1
1 Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
2 Department of Genetics, Institute of Medical Science, University of Tokyo, Japan
Circulation, Volume 105, Issue 9, Pages 1110-1115, 5 Mar 2002

Anti-Monocyte Chemoattractant Protein-1 Gene Therapy Limits Progression and Destabilization of Established Atherosclerosis in Apolipoprotein E-Knockout Mice
Shujiro Inoue 1, Kensuke Egashira 1, Weihua Ni 1, Shiro Kitamoto 1, Makoto Usui 1, Kisho Otani 1, Minako Ishibashi 1, Ken-ichi Hiasa 1, Ken-ichi Nishida 2 and Akira Takeshita 1
1 Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
2 New Product Research Laboratories, Dai-ichi Pharmaceutical Co, Tokyo, Japan
Circulation, Volume 106, Issue 21, Pages 2700-2706, 19 November 2002

Early subdivisions in the neural plate define distinct competence for inductive signals
Daisuke Kobayashi 1, Makoto Kobayashi 2, Ken Matsumoto 3, Toshihiko Ogura 3, Masato Nakafuku 1 and Kenji Shimamura 1
1 Department of Neurobiology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
2 Institute of Basic Medical Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan
3 Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0101, Japan
Development, Volume 129, Issue 1, Pages 83-93, January 2002

Bimodal functions of Notch-mediated signaling are involved in neural crest formation during avian ectoderm development
Yukinori Endo 1, Noriko Osumi 1 and Yoshio Wakamatsu 1, 2
1 Department of Developmental Neurobiology, Graduate School of Medicine, Tohoku University, Sendai, Miyagi 980-8575, Japan
2 PRESTO, Japan Science and Technology Corporation, Japan
Development, Volume 129, Issue 4, Pages 863-873, February 2002

Pax6 regulates specification of ventral neurone subtypes in the hindbrain by establishing progenitor domains
Masanori Takahashi 1 and Noriko Osumi 1 (E-mail:
osumi@mail.cc.tohoku.ac.jp)
1 Department of Developmental Neurobiology, Tohoku University Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan
Development, Volume 129, Issue 6, Pages 1327-1338, March 2002

The chicken RaxL gene plays a role in the initiation of photoreceptor differentiation
C.-M. Amy Chen 1 and Constance L. Cepko 1 (E-mail:
cepko@genetics.med.harvard.edu)
1 Department of Genetics, Harvard Medical School, Howard Hughes Medical Institute, 200 Longwood Avenue, Boston, MA 02115, USA
Development, Volume 129, Issue 23, Pages 5363-5375, December 2002

Efficient ectopic gene expression targeting chick mesoderm
Kerby C. Oberg 1, 2, (E-mail:
koberg@som.llu.edu), Charmaine U. Pira 1, Jean-Pierre Revelli 3, Beate Ratz 4, Estuardo Aguilar-Cordova 5, 6, 7 and Gregor Eichele 3, 4
1 Department of Pathology and Human Anatomy, Loma Linda University, Loma Linda, California
2 Department of Pathology, Baylor College of Medicine, Houston, Texas
3 Department of Biochemistry, Baylor College of Medicine, Houston, Texas
4 Max-Planck Institute for Experimental Endocrinology, Hannover, Germany
5 Department of Pediatrics, Baylor College of Medicine, Houston, Texas
6 Department of Radiotherapy, Baylor College of Medicine, Houston, Texas
7 Harvard Gene Therapy Initiative, Harvard Medical School, Boston, Massachusetts
Developmental Dynamics, Volume 224, Issue 3, Pages 291-302, July 2002

Manipulating gene expressions by electroporation in the developing brain of mammalian embryos
M. Takahashi 1, K. Sato 2, T. Nomura 1 and N. Osumi 1 (E-mail:
osumi@mail.cc.tohoku.ac.jp)
1 Department of Developmental Neurobiology, Tohoku University Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan
2 Department of Neurosurgery, Tohoku University Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan
Differentiation, Volume 70, Issue 4-5, Pages 155-162, June 2002

Improved mRNA Electroporation Method for Xenopus Neurula Embryos
Satoru Sasagawa 1, Takashi Takabatake 2, Yuka Takabatake 1, Tatsuo Muramatsu 3, and Kazuhito Takeshima 2 (E-mail:
c42584a@nucc.cc.nagoya-u.ac.jp)
1 Graduate School of Human Informatics, Nagoya University, Nagoya, Japan
2 Radioisotope Research Center, Nagoya University, Nagoya, Japan
3 Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan
Genesis, Volume 33, Issue 2, Pages 81-85, June 2002

Axes establishment during eye morphogenesis in Xenopus by coordinate and antagonistic actions of BMP4, Shh, and RA
Satoru Sasagawa 1, Takashi Takabatake 2, Yuka Takabatake 1, Tatsuo Muramatsu 3, Kazuhito Takeshima 2 (E-mail:
c42584a@nucc.cc.nagoya-u.ac.jp)
1 Graduate School of Human Informatics, Nagoya University, Nagoya, Japan
2 Radioisotope Research Center, Nagoya University, Nagoya, Japan
3 Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan
Genesis, Volume 33, Issue 2, Pages 86-96, June 2002

Induction of dental pulp stem cell differentiation into odontoblasts by electroporation-mediated gene delivery of growth/differentiation factor 11 (Gdf11)
Nakashima M 1, Mizunuma K 1, Murakami T 1 and Akamine A 1
1 Department of Clinical Oral Molecular Biology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka, Japan.
Gene Therapy, Volume 9, Number 12, Pages 814-818, June 2002

Attenuated acute liver injury in mice by naked hepatocyte growth factor gene transfer into skeletal muscle with electroporation
F Xue 1, T Takahara 1, Y Yata 1, M Minemura 1, C Y Morioka 1, S Takahara 2, E Yamato 3, K Dono 4 and A Watanabe 1
1 Third Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan
2 Department of Urology, Osaka University Medical School, Osaka, Japan
3 Department of Nutrition and Physiological Chemistry, Osaka University Medical School, Osaka, Japan
4 Department of Surgery and Clinical Oncology, Osaka University Medical School, Osaka, Japan
Gut, Volume 50, Number 4, Pages 558-562, April 2002

Tie2 vascular endothelial receptor expression and function in hepatocellular carcinoma
Shinji Tanaka 1 (E-mail:
shinjit@surg2.med.kyushu-u.ac.jp), Keishi Sugimachi 1, Yo-ichi Yamashita 1, Takefumi Ohga 1, Ken Shirabe 1, Mitsuo Shimada 1, Jack R. Wands 3, Keizo Sugimachi 1, 2
1 Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
2 Station for Collaborative Research, Kyushu University, Fukuoka, Japan
3 Liver Research Center, Rhode Island Hospital, Brown University School of Medicine, Providence, RI
Hepatology, Volume 35, Issue 4, Pages 861-867, April 2002

Electroporation-Mediated Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)/Apo2L Gene Therapy for Hepatocellular Carcinoma
Yo-Ichi Yamashita 1, Mitsuo Shimada 1, Shinji Tanaka 1, Masahiro Okamamoto 1, Jun-Ichi Miyazaki 2 and Keizo Sugimachi 1
1 Department of Surgery and Science, Graduate School of Medical Sciences, and Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan
2 Division of Stem Cell Regulation Research (G6), Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan
Human Gene Therapy, Volume 13, Number 2, Pages 275-286, January 2002

In Vivo Gene Transfer into Muscle via Electro-Sonoporation
Yo-Ichi Yamashita 1, Mitsuo Shimada 1, Katsuro Tachibana 2, Norifumi Harimoto 1, Eiji Tsujita 1, Ken Shirabe 1, Jun-Ichi Miyazaki 3 and Keizo Sugimachi 1
1 Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan
2 Department of Anatomy, Fukuoka University School of Medicine, Fukuoka 814-0180, Japan
3 Division of Stem Cell Regulation Research, G6, Osaka University Medical School, Osaka 565-0871, Japan
Human Gene Therapy, Volume 13, Number 17, Pages 2079-2084, November 2002

Gene Therapy for Mitochondrial Disease by Delivering Restriction Endonuclease SmaI into Mitochondria
Masashi Tanaka 1, 2, Harm-Jan Borgeld 1, 2, Jin Zhang 1, 2, Shin-ichi Muramatsu 3, Jian-Sheng Gong 1, 2, Makoto Yoneda 4, Wakako Maruyama 5, Makoto Naoi 2, Tohru Ibif Ko Sahashi 6, Masayo Shamoto 5, Noriyuki Fuku 1, 7, Miyuki Kurata 1, Yoshiji Yamada 1, 2, Kumi Nishizawa 1, Yukihiro Akao 1, 2, Nobuko Ohishi 2, Shigeaki Miyabayashi 8, Hiraku Umemoto 9, Tatsuo Muramatsu 9, Koichi Furukawa 10, Akihiko Kikuchi 11, Imaharu Nakano 3, Keiya Ozawa 12 and Kunio Yagi 1, 2
1 Department of Gene Therapy, Gifu International Institute of Biotechnology
2 Institute of Applied Biochemistry, Mitake
3 Department of Neurology, Jichi Medical School, Tochigi
4 Second Department of Internal Medicine, Fukui Medical University, Fukui
5 Laboratory of Biochemistry and Metabolism, Department of Basic Gerontology, National Institute for Longevity Sciences, Obu
6 Neurology Section, Department of Internal Medicine, Aichi Medical University, Aichi
7 Japan Science and Technology Corporation, Tokyo
8 Department of Pediatrics, Sendai National Hospital, Sendai
9 Department of Applied Genetics and Physiology, Graduate School of Bioagricultural Sciences, Nagoya University
10 Department of Biochemistry, Graduate School of Medical Sciences, Nagoya University
11 Department of Medical Mycology, Graduate School of Medical Sciences, Nagoya University, Nagoya
12 Division of Genetic Therapeutics, Center for Molecular Medicine, Jichi Medical School, Tochigi, Japan
Journal of Biomedical Science, Volume 9, Number 6, Pages 534-541, 2002

Anti-Monocyte Chemoattractant Protein-1 Gene Therapy Protects Against Focal Brain Ischemia in Hypertensive Rats
Yasuhiro Kumai 1, Hiroaki Ooboshi 1, Junichi Takada 1, Masahiro Kamouchi 1, Takanari Kitazono 1, Kensuke Egashira 2, Setsuro Ibayashi 1 and Mitsuo Iida 1
1 Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
2 Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Journal of Cerebral Blood Flow & Metabolism, Volume 24, Issue 12, Pages 1359-1368, December 2004

Introduction and expression of foreign genes in cultured mouse embryonic gonads by electroporation
Yuri Nakamura 1, Miwako Yamamoto 1 and Yasuhisa Matsui 1 (E-mail:
ymatsui@lab.mch.pref.osaka.jp)
1 Department of Molecular Embryology, Research Institute, Osaka Medical Center for Maternal and Child Health, Izumi, Japan
Reproduction, Fertility and Development, Volume 14, Number 5, Pages 259-265, 22 August 2002

In vitro analysis of the origin, migratory behavior, and maturation of cortical pyramidal cells
Yumiko Hatanaka 1, 2 (E-mail:
yumiko@nibb.ac.jp) and Fujio Murakami 1, 2, 3 (E-mail: murakami@fbs.osaka-u.ac.jp)
1 Division of Behavior and Neurobiology, National Institute for Basic Biology, Okazaki, Aichi 444-8585, Japan
2 CREST, Japan Science and Technology, Kawaguchi, Saitama 332-0012, Japan
3 Laboratory of Neuroscience, Graduate School of Frontier Biosciences, Osaka University, 1-3 Machikaneyama, Toyonaka, Osaka 560-8531, Japan
The Journal of Comparative Neurology, Volume 454, Issue 1, Pages 1-14, 2 December 2002

Targeting Axons to Specific Fiber Tracts In Vivo by Altering Cadherin Expression
Ullrich Treubert-Zimmemann 1 (E-mail:
ullrich.treubert@uni-essen.de), Dominik Heyers 1 and Christoph Redies 1
1 Institute of Anatomy, University of Essen Medical School, D-45122 Essen, Germany
The Journal of Neuroscience, Volume 22, Issue 17, Pages 7617-7626, 1 September 2002

[2001]
Electroporation-mediated Interleukin-12 Gene Therapy for Hepatocellular Carcinoma in the Mice Model
Yo-ichi Yamashita 1 (E-mail:
yamashi@surg2.med.kyushu-u.ac.jp), Mitsuo Shimada 1, Hirofumi Hasegawa 1, Ryosuke Minagawa 2, Tatsuya Rikimaru 1, Takayuki Hamatsu 1, Shinji Tanaka 1, Ken Shirabe 1, Jun-ichi Miyazaki 3 and Keizo Sugimachi 1
1 Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582
2 Department of Immunology, Medical Institute of Bioregulation, Fukuoka 812-8582
3 Department of Nutrition and Physiological Chemistry, Osaka University Medical School, Osaka 565-0871
Cancer Research, Volume 61, Issue 3, Pages 1005-1012, 1 February 2001

Protection Against Autoimmune Myocarditis by Gene Transfer of Interleukin-10 by Electroporation
Kenichi Watanabe 1, Mikio Nakazawa 3, Koichi Fuse 4, Haruo Hanawa 4, Makoto Kodama 4, Yoshifusa Aizawa 4, Toshio Ohnuki 2, Fumitake Gejyo 5, Hiroki Maruyama 5 and Jun-ichi Miyazaki 6
1 Department of Clinical Pharmacology, Niigata College of Pharmacy, Niigata, Japan
2 Department of Pharmacology, Niigata College of Pharmacy, Niigata, Japan
3 Department of Medical Technology, School of Health Sciences, Niigata University School of Medicine, Niigata, Japan
4 Division of Cardiology, Niigata Graduate School of Medicine and Dental Science, Niigata, Japan
5 Division of Clinical Nephrology and Rheumatology, Niigata Graduate School of Medicine and Dental Science, Niigata, Japan
6 Department of Nutrition and Physiological Chemistry, Osaka University Graduate School of Medicine, Osaka, Japan
Circulation, Volume 104, Issue 10, Pages 1098-1100, 4 September 2001

Inductive signal and tissue responsiveness defining the tectum and the cerebellum
Tatsuya Sato 1, Isato Araki 1, * and Harukazu Nakamura 1 (E-mail:
nakamura@idac.tohoku.ac.jp)
1 Department of Molecular Neurobiology, Institute of Development, Aging and Cancer, Seiryo-machi 4-1, Aoba-ku, Sendai 980-8575, Japan
* Present address: Department of Neurobiology, University of Heidelberg, Im Neuenheimer Feld 364, D-69120 Heidelberg, Germany
Development, Volume 128, Issue 13, Pages 2461-2469, July 2001

Long-term production of erythropoietin after electroporation-mediated transfer of plasmid DNA into the muscles of normal and uremic rats
H Maruyama 1, K Ataka 1, F Gejyo 1, N Higuchi 1, Y Ito 1, H Hirahara 2, I Imazeki 3, M Hirata 4, F Ichikawa 5, T Neichi 5, H Kikuchi 1, M Sugawa 6 and J Miyazaki 7
1 Department of Medicine (II), Niigata University School of Medicine, Niigata, Japan
2 Department of Surgery (II), Niigata University School of Medicine, Niigata, Japan
3 Product Research Laboratory, Chugai Pharmaceutical Co., Ltd., Tokyo, Japan
4 Pharmaceutical Research Laboratory, Chugai Pharmaceutical Co., Ltd., Tokyo, Japan
5 Product Planning and Business Development, Chugai Pharmaceutical Co., Ltd., Tokyo, Japan
6 Pharmaceutical Technology Laboratory, Chugai Pharmaceutical Co., Ltd., Tokyo, Japan
7 Department of Nutrition and Physiological Chemistry, G6, Osaka University Medical School, Japan
Gene Therapy, Volume 8, Number 6, Pages 461-468, March 2001

In vivo electroporation-mediated transfer of interleukin-12 and interleukin-18 genes induces significant antitumor effects against melanoma in mice
T Kishida 1, H Asada 1, E Satoh 1, S Tanaka 2, M Shinya 1, H Hirai 1, M Iwai 2, H Tahara 3, J Imanishi 1 and O Mazda 1
1 Department of Microbiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
2 Third Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan
3 Department of Surgery, Institute of Medical Science, University of Tokyo, Tokyo, Japan
Gene Therapy, Volume 8, Number 16, Pages 1234-1240, August 2001

Skin-targeted gene transfer using in vivo electroporation.
H Maruyama 1, K Ataka 1, N Higuchi 1, F Sakamoto 2, F Gejyo 1 and J Miyazaki 3
1 Department of Medicine (II), Niigata University School of Medicine, Niigata, Japan
2 Department of Dermatology, Niigata University School of Medicine, Niigata, Japan
3 Department of Nutrition and Physiological Chemistry, Osaka University Medical School, Suita, Japan
Gene Therapy, Volume 8, Number 23, Pages 1808-1812, December 2001

Elevated gastrin secretion by in vivo gene electroporation in skeletal muscle
Akihiro Yasui 1, Koji Oda 2, Hirotoshi Usunomiya 3, Kenichi Kakudo 3, Takayuki Suzuki 4, Toyonobu Yoshida 4, Hyi-Man Park 4, Kazuteru Fukazawa 4 and Tatsuo Muramatsu 4
1 Department of Surgery, Chubu National Hospital, Ohbu 474-8511
2 Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya 466-8550
3 Second Department of Pathology, Wakayama Medical College, Wakayama 640-8155
4 Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan
International Journal of Molecular Medicine, Volume 8, Number 5, Pages 489-494, November 2001

Infectivity-Enhancing Antibodies to Ebola Virus Glycoprotein
Ayato Takada 1, 2, *, Shinji Watanabe 2, Katsunori Okazaki 1, Hiroshi Kida 1, and Yoshihiro Kawaoka 2, 3 (E-mail:
kawaokay@svm.vetmed.wisc.edu)
1 Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818
2 Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin 53706
3 Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo 108-8639, Japan
* Present address: Institute of Medical Science, University of Tokyo, Tokyo, Japan
Journal of Virology, Volume 75, Number 5, Pages 2324-2330, March 2001

Gene Transfer into Cultured Mammalian Embryos by Electroporation
Noriko Osumi 1, 2 (E-mail:
osumi@mail.cc.tohoku.ac.jp) and Takayoshi Inoue 2
1 Department of Neural Development, Tohoku University Graduate School of Medicine, 2-1, Seiryo-cho, Aoba-ku, Sendai, Miyagi, 980-8575, Japan
2 Division of Biochemistry and Cell Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 4-1-1, Ogawahigashi, Kodaira, Tokyo, 187-8502, Japan
Methods, Volume 24, Issue 1, Pages 35-42, May 2001

Efficient in utero gene transfer system to the developing mouse brain using electroporation: visualization of neuronal migration in the developing cortex
H. Tabata 1 and K. Nakajima 1, 2 (E-mail:
kazunori@jikei.ac.jp)
1 Department of Molecular Neurobiology, Institute of DNA Medicine, Jikei University School of Medicine, Minato-ku, Tokyo 105-8461, Japan
2 Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Corporation (JST), Kawaguchi, Saitama 332-0012, Japan
Neuroscience, Volume 103, Issue 4, Pages 865-872, 4 April 2001

Ventroptin: A BMP-4 Antagonist Expressed in a Double-Gradient Pattern in the Retina
Hiraki Sakuta 1, Ryoko Suzuki 1, Hiroo Takahashi 1, Akira Kato 1, Takafumi Shintani 1, Shun-ichiro Iemura 1, Takamasa S. Yamamoto 1, Naoto Ueno 1 and Masaharu Noda 1
1 Division of Molecular Neurobiology, National Institute for Basic Biology, The Graduate University for Advanced Studies, 38 Nishigonaka, Myodaiji-cho, Okazaki 444-8585, Japan.
Science, Volume 293, Issue 5527, Pages 111-115, 6 July 2001

Roles of the Basic Helix-Loop-Helix Genes Hes1 and Hes5 in Expansion of Neural Stem Cells of the Developing Brain
Toshiyuki Ohtsuka 1, Masami Sakamoto 1, Francois Guillemot 2 and Ryoichiro Kageyama 1
1 Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan
2 Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERM, Universite Louis Pasteur, College de France, 67404 Illkirch, Centre de l'Universite de Strasbourg, France
The Journal of Biological Chemistry, Volume 276, Issue 32, Pages 30467-30474, 10 August 2001

 


[2000]
Production of chicken chimeras by fusing blastodermal cells with electroporation
S. Aritomi 1 and N. Fujihara 1 (E-mail:
nfujiha@agr.kyushu-u.ac.jp)
1 Division of Animal Resource Science, Faculty of Agriculture, Kyushu University Graduate School, Fukuoka 812-8581, Japan
Asian Journal of Andrology, Volume 2, Issue 4, Pages 271-275, December 2000

Control of chick tectum territory along dorsoventral axis by Sonic hedgehog
Yuji Watanabe 1 (E-mail:
yuji@idac.tohoku.ac.jp) and Harukazu Nakamura 1
1 Department of Molecular Neurobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai 980-8575, Japan
Development, Volume 127, Issue 5, Pages 1131-1140, March 2000

Hes1 is a negative regulator of inner ear hair cell differentiation
JL Zheng 1, J Shou 1, F Guillemot 1, R Kageyama 1 and WQ Gao 1 (E-mail:
gao@gene.com)
1 Department of Neuroscience, Genentech, Inc., South San Francisco, CA 94080, USA
Development, Volume 127, Issue 21, Pages 4551-4560, November 2000

Misexpression of genes in brain vesicles by in ovo electroporation
Harukazu Nakamura 1, Yuji Watanabe 1 and Jun-ichi Funahashi 1
1 Department of Molecular Neurobiology, Institute of Development, Aging and Cancer, Tohoku University, Seiryo-machi 4-1, Aoba-ku, Sendai 980-8575, Japan
Development Growth & Differentiation, Volume 42, Issue 3, Page 199-201, June 2000

Enhancement of antitumor effect of bleomycin by low-voltage in vivo electroporation: A study of human uterine leiomyosarcomas in nude mice
Akiko Horiuchi 1, Toshio Nikaido 1 (E-mail:
tnikaido@hsp.md.shinshu-u.ac.jp), Junji Mitsushita 1, Toshihiko Toki 1, Ikuo Konishi 1, Shingo Fujii 3
1 Department of Obstetrics and Gynecology, Shinshu University School of Medicine, Matsumoto, Japan
2 Department of Organ Regeneration, Institute of Organ Transplants, Reconstructive Medicine and Tissue Engineering, Shinshu University Graduate School of Medicine, Matsumoto, Japan
3 Department of Gynecology and Obstetrics, Faculty of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan
International Journal of Cancer, Volume 88, Issue 4, Pages 640-644, November 2000

Expression Regulation of Hyaluronan Synthase in Corneal Endothelial Cells
Tomohiko Usui 1, Shiro Amano 1, Tetsuro Oshika 1, Kaori Suzuki 1, Kazunori Miyata 2, Makoto Araie 1, Paraskevi Heldin 3 and Hidetoshi Yamashita 4
1 Department of Ophthalmology, Faculty of Medicine, University of Tokyo
2 Miyata Eye Hospital, Miyazaki, Japan
3 Department of Medical and Physiological Chemistry, Uppsala University, Biomedical Center, Sweden
4 Department of Ophthalmology, Yamagata University, School of Medicine, Japan
Investigative Ophthalmology and Visual Science, Volume 41, Number 11, Pages 3261-3267, October 2000

Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears
Zheng JL 1 and Gao WQ. 1 (E-mail:
gao@gene.com)
1 Department of Neuroscience, MS #72, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.
Nature Neuroscince, Volume 3, Number 6, Pages 580-586, June 2000

Up-regulation of Protein-disulfide Isomerase in Response to Hypoxia/Brain Ischemia and Its Protective Effect against Apoptotic Cell Death
Shinji Tanaka 1, Takashi Uehara 1 and Yasuyuki Nomura 1
1 The Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan
The Journal of Biological Chemistry, Volume 275, Issue 14, Pages 10388-10393, 7 April 2000

[1999]
Engrailed defines the position of dorsal di-mesencephalic boundary by repressing diencephalic fate
Isato Araki 1 (E-mail:
iaraki@idac.tohoku.ac.jp) and Harukazu Nakamura 1
1 IDAC, Tohoku University, Sendai 980-8575, Japan
Development, Volume 126, Issue 22, Pages 5127-5135, November 1999

'Shocking' developments in chick embryology: electroporation and in ovo gene expression
Nobue Itasaki 1, Sophie Bel-Vialar 1 and Robb Krumlauf 1
1 Laboratory of Developmental Neurobiology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
Nature Cell Biology, Volume 1, Issue 8, Pages E203-E207, December 1999

Misexpression of the Emx-Related Homeobox Genes cVax and mVax2 Ventralizes the Retina and Perturbs the Retinotectal Map
Dorothea Schulte 1, Takahisa Furukawa 1, Maureen A. Peters 1, Christine A. Kozak 2 and Constance L. Cepko 1 (E-mail:
cepko@rascal.med.harvard.edu)
1 Department of Genetics and, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
2 Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland 20892, USA
Neuron, Volume 24, Issue 3, Pages 541-553, November 1999

 

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