[2006]
Caspase redundancy and release of mitochondrial apoptotic factors characterize interdigital apoptosis
V. Zuzarte-Luis ¹, M. T. Berciano ¹, M. Lafarga ¹ and J. M. Hurle ^{1, 2} (E-mail: hurlej@unican.es)
¹ Departamento de Anatomia y Biologia Celular, Facultad de Medicina, Universidad de Cantabria, Santander, 39011, Spain
² Departamento de Anatomia y Biologia Celular, Facultad de Medicina, C/Cardenal Herrera Oria s/n, Santander, 39011, Spain
Apoptosis, Volume 11, Number 5, Pages 701-715, May 2006

Isolation and Characterization of Vasohibin-2 as a Homologue of VEGF-Inducible Endothelium-Derived Angiogenesis Inhibitor Vasohibin
Takumi Shibuya ¹, Kazuhide Watanabe ^{1, 4}, Hiroshi Yamashita ¹, Kazue Shimizu ¹, Hiroki Miyashita ¹, Mayumi Abe ^{1, *}, Takuya Moriya ², Hideki Ohta ³, Hikaru Sonoda ³, Tooru Shimosegawa ⁴, Koichi Tabayashi ⁵, Yasufumi Sato ¹ (E-mail: y-sato@idac.tohoku.ac.jp)
¹ Department of Vascular Biology, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan
² Department of Pathology, Tohoku University Hospital, Sendai, Japan
³ Diagnostics Science Division, Shionogi & Co, Ltd, Toyonaka, Japan
⁴ Department of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan
⁵ Department of Cardiovascular Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan
^* Present address: Department of Nanomedicine, Tokyo Medical and Dental University, Tokyo, Japan
Arteriosclerosis, Thrombosis, and Vascular Biology, Volume 26, Issue 5, Pages 1051-1057, May 2006

Compensation by tumor suppressor genes during retinal development in mice and humans
Stacy L Donovan ¹, Brett Schweers ¹, Rodrigo Martins ¹, Dianna Johnson ² and Michael A Dyer ^{1, 2} (E-mail: michael.dyer@stjude.org)
¹ Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA
² Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
BMC Biology, Volume 4, Issue 14, 3 May 2006

Simultaneous gene transfer of bone morphogenetic protein (BMP) -2 and BMP-7 by in vivo electroporation induces rapid bone formation and BMP-4 expression
Mariko Kawai ¹ (E-mail: marikoka@md.okayama-u.ac.jp), Kazuhisa Bessho ² (E-mail: bes@kuhp.kyoto-u.ac.jp), Hiroki Maruyama ³ (E-mail: hirokim@med.niigata-u.ac.jp), Jun-ichi Miyazaki ⁴ (E-mail: jimiyaza@nutri.med.osaka-u.ac.jp) and Toshio Yamamoto ¹ (E-mail: ytoshio@md.okayama-u.ac.jp)
¹ Department of Oral Morphology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan
² Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan
³ Division of Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8120, Japan
⁴ Division of Stem Cell Regulation Research, Osaka University Medical School, Osaka 565-0871, Japan
BMC Musculoskeletal Disorders, Volume 7, Issue 62, 3 August 2006

In vivo Evidence for Radial Migration of Neurons by Long-Distance Somal Translocation in the Developing Ferret Visual Cortex
Victor Borrell ^{1, *} (E-mail: vborrell@umh.es), Brian K. Kaspar ², Fred H. Gage ² and Edward M. Callaway ^1
1 Systems Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA
² Laboratory of Genetics, The Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA
^* President address: Instituto de Neurociencias de Alicante, Consejo Superior de Investigaciones Cientificas, Universidad Miguel Hernandez, Sant Joan d'Alacant, Spain
Cerebral Cortex, Volume 16, Number 11, Pages 1571-1583, November 2006

Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development
Daisuke Sakai ¹, Takashi Suzuki ¹, Noriko Osumi ¹ and Yoshio Wakamatsu ² (E-mail: wakasama@mail.tains.tohoku.ac.jp)
¹ Center for Translational and Advanced Animal Research on Human Diseases, Division of Developmental Neuroscience, Graduate School of Medicine, Tohoku University, Sendai, Miyagi 980-8575, Japan
² Department of Developmental Neurobiology, Graduate School of Medicine, Tohoku University, Sendai, Miyagi 980-8575, Japan
Development, Volume 133, Issue 7, Pages 1323-1333, April 2006

Pax6-dependent boundary defines alignment of migrating olfactory cortex neurons via the repulsive activity of ephrin A5
Tadashi Nomura ¹, Johan Holmberg ², Jonas Frisen ² and Noriko Osumi ^{1, 3} (E-mail: osumi@mail.tains.tohoku.ac.jp)
¹ Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research (CTTAR), Tohoku University School of Medicine, 2-1, Seiryo-machi, Aoba-ku, 980-8575, Japan
² Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden
³ Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Kawaguchi, 332-0012, Japan
Development, Volume 133, Issue 7, Pages 1335-1345, April 2006

Multidirectional and multizonal tangential migration of GABAergic interneurons in the developing cerebral cortex
Daisuke H. Tanaka ¹, Kazunori Maekawa ¹, Yuchio Yanagawa ², Kunihiko Obata ³ and Fujio Murakami ¹ (E-mail: murakami@fbs.osaka-u.ac.jp)
¹ Graduate School of Frontier Biosciences, Osaka University, and SORST, Japan
Science and Technology Corporation (JST), Yamadaoka 1-3, Suita, Osaka 560-8531, Japan
² Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi 371-8511, Japan
³ Neural Circuit Mechanism Group, BSI, RIKEN, Hirosawa 2-1, Wako, 351-0198, Japan
Development, Volume 133, Issue 11, Pages 2167-2176, June 2006

An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation
Shu-Zong Wang ¹, Jennifer Dulin ¹, Heng Wu ¹, Edward Hurlock ¹, Sang-Eun Lee ¹, Kyle Jansson ¹ and Q. Richard Lu ¹ (E-mail: qrichard.lu@utsouthwestern.edu)
¹ Center for Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Development, Volume 133, Issue 17, Pages 3389-3398, September 2006

PINCH-1 expression during early avian embryogenesis: Implications for neural crest and heart development
Brad J. Martinsen ¹ (E-mail: marti198@umn.edu), Ann N. Neumann ¹, Allison J. Frasier ¹, Clare V.H. Baker ², Catherine E. Krull ³, Jamie L. Lohr ^1
1 Department of Pediatrics, Division of Pediatric Cardiology, University of Minnesota School of Medicine, Minneapolis, Minnesota
² Department of Anatomy, University of Cambridge, Cambridge, England
³ Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan
Developmental Dynamics, Volume 235, Issue 1, Pages 152-162, January 2006

Inhibition of zebrafish fin regeneration using in vivo electroporation of morpholinos against fgfr1 and msxb
Ryan Thummel ¹ (E-mail: thummel.1@nd.edu), Shan Bai ², Michael P. Sarras Jr ², Peizhen Song ¹, Jeffrey McDermott ¹, Jeffrey Brewer ¹, Martin Perry ¹, Xiaoming Zhang ², David R. Hyde ³, Alan R. Godwin ^1
1 Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas
² Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas
³ Department of Biological Sciences and Center for Zebrafish Research, University of Notre Dame, Notre Dame, Indiana
Developmental Dynamics, Volume 235, Issue 2, Pages 336-346, February 2006

Basic helix-loop-helix gene Hes6 delineates the sensory hair cell lineage in the inner ear
Dong Qian ¹, Kristen Radde-Gallwitz ¹, Michael Kelly ¹, Bjorn Tyrberg ², Jaesang Kim ³, Wei-Qiang Gao ⁴, Ping Chen ¹ (E-mail: pchen@cellbio.emory.edu)
¹ Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, USA
² Burnham Institute, La Jolla, California, USA
³ Division of Molecular Life Sciences, Ewha Womans University, Seoul, Korea
⁴ Department of Molecular Biology, Genentech, South San Francisco, California, USA
Developmental Dynamics, Volume 235, Issue 6, Pages 1689-1700, June 2006

Electroporation and EGFP labeling of gastrulating quail embryos
Cheng Cui ¹, Rusty Lansford ², Mike B. Filla ¹, Charles D. Little ¹, Tracey J. Cheuvront ¹, Brenda J. Rongish ¹ (E-mail: brongish@kumc.edu)
¹ Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas, USA
² Biology Division, California Institute of Technology, Pasadena, California, USA
Developmental Dynamics, Volume 235, Issue 10, Pages 2802-2810, October 2006

Thyroid hormone-induced expression of a bZip-containing transcription factor activates epithelial cell proliferation during Xenopus larval-to-adult intestinal remodeling
Masayuki Ikuzawa ¹, Katsuhiko Shimizu ², Shigeki Yasumasu ¹, Ichiro Iuchi ¹, Yun-Bo Shi ³ and Atsuko Ishizuya-Oka ⁴ (E-mail: a-oka@nms.ac.jp)
¹ Life Science Institute, Sophia University, Chiyoda-ku, Tokyo 102-8554, Japan
² Yoshizato Project, CLUSTER, Hiroshima Prefectural Institute of Industrial Science and Technology, Higashi-Hiroshima, Hiroshima 739-0046, Japan
³ Laboratory of Gene Regulation and Development, National Institute of Child Health and Human Development, Bethesda, MD 20892-5431, USA
⁴ Department of Biology, Nippon Medical School, Kawasaki Kanagawa, 211-0063, Japan
Development Genes and Evolution, Volume 216, Number 3, Pages 109-118, March 2006

Role of Gbx2 and Otx2 in the formation of cochlear ganglion and endolymphatic duct
Hiromitsu Miyazaki ^{1, 2}, Toshimitsu Kobayashi ², Harukazu Nakamura ^{1, 3}, and Jun-ichi Funahashi ¹ (E-mail: junichif@idac.tohoku.ac.jp)
¹ Department of Molecular Neurobiology, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan
² Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan
³ Graduate School of Life Sciences, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan
Development, Growth & Differentiation, Volume 48, Issue 7, Page 429-438, September 2006

Negative feedback predominates over cross-regulation to control ERK MAPK activity in response to FGF signalling in embryos
Terence Gordon Smith ¹ (E-mail: tel_smith@yahoo.co.uk), Maria Karlsson ², J. Simon Lunn ¹, Maxwell C. Eblaghie ¹, Iain D. Keenan ², Elizabeth R. Farrell ¹, Cheryll Tickle ¹, Kate G. Storey ¹ and Stephen M. Keyse ^2
1 Division of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
² Cancer Research UK Molecular Pharmacology Unit, Biomedical Research Centre, Level 5, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, United Kingdom
FEBS Letters, Volume 580, Issue 17, Pages 4242-4245, 24 July 2006

Sustained expression of Epstein-Barr virus episomal vector mediated factor VIII in vivo following muscle electroporation
W. H. Mei ¹, G. Q. Qian ¹, X. Q. Zhang ¹, P. Zhang ¹ and J. LU ¹ (E-mail: jianlu@shsmu.edu.cn)
¹ Department of Biochemistry and Molecular Biology, School of Medicine, Shanghai JiaoTong University, Shanghai, China
Haemophilia, Volume 12, Issue 3, Page 271-279, May 2006

Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells
Agnes G.S.H. van Rossum ¹, Wendy M. Aartsen ¹, Jan Meuleman ¹, Jan Klooster ², Anna Malysheva ¹, Inge Versteeg ¹, Jean-Pierre Arsanto ³, Andre Le Bivic ³ and Jan Wijnholds ¹ (Email: j.wijnholds@nin.knaw.nl)
¹ Department of Neuromedical Genetics, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Meibergdreef 47, 1105 BA Amsterdam, The Netherlands
² Department of Retinal Signal Processing, The Netherlands Institute for Neuroscience (NIN), Royal Netherlands Academy of Arts and Sciences (KNAW), Meibergdreef 47, 1105 BA Amsterdam, The Netherlands
³ UMR CNRS 6216, Institute of Developmental Biology of Marseille-Luminy, Faculte des Sciences de Luminy, Case 907, 13288 Marseille Cedex 09, France
Human Molecular Genetics, Volume 15, Issue 18, Pages 2659-2672, 15 September 2006

Activator protein 1-mediated transcriptional regulation strategy sustains long-term expression of a xenogeneic gene product in vivo : An implication for gene therapy targeting congenital protein deficiencies
Shin Sasaki ¹, James M. Smith ², Keiko Takase ¹, Kenji Okuda ¹, Norihisa Ishii ³ and Fumihiko Takeshita ¹ (E-mail: takesita@yokohama-cu.ac.jp)
¹ Department of Molecular Biodefense Research, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan
² Antibody Systems, Inc. Hurst, Texas 76054, USA
³ Department of Bioregulation, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo 189-0002, Japan
International journal of molecular medicine, Volume 18, Number 2, Pages 289-297, August 2006

L1, beta1 integrin, and cadherins mediate axonal regeneration in the embryonic spinal cord
Murray Blackmore ¹ (E-mail: mblackmore@med.miami.edu) and Paul C. Letourneau ^1
1 Department of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455
Journal of Neurobiology, Volume 66, Issue 14, Pages 1564-1583, December 2006

Toll-Like Receptor Adaptor Molecules Enhance DNA-Raised Adaptive Immune Responses against Influenza and Tumors through Activation of Innate Immunity
Fumihiko Takeshita ¹ (E-mail: takesita@yokohama-cu.ac.jp), Toshiyuki Tanaka ¹, Tomoko Matsuda ¹, Miyuki Tozuka ¹, Kouji Kobiyama ¹, Sukumar Saha ¹, Kiyohiko Matsui ¹, Ken J. Ishii ², Cevayir Coban ², Shizuo Akira ², Norihisa Ishii ³, Koichi Suzuki ³, Dennis M. Klinman ⁴, Kenji Okuda ¹ and Shin Sasaki ^1
1 Department of Molecular Biodefense Research, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan
² ERATO, Akira Innate Immunity Program, Japan Science and Technology Agency, Osaka 565-0871, Japan
³ Department of Bioregulation, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo 189-0002, Japan
⁴ Section of Retroviral Immunology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 208924
Journal of Virology, Volume 80, Number 13, Pages 6218-6224, July 2006

Gene therapy with TRAIL against renal cell carcinoma
Hiroki Matsubara ¹, Yoichi Mizutani ¹, Fumiya Hongo ¹, Hiroyuki Nakanishi ¹, Yasunori Kimura ¹, So Ushijima ¹, Akihiro Kawauchi ¹, Takahiro Tamura ², Tsuneaki Sakata ² and Tsuneharu Miki ^1
1 Department of Urology, Kyoto Prefectural University of Medicine, Kyoto, Japan
² Shionogi Institute for Medical Science, Osaka, Japan
Molecular Cancer Therapeutics, Volume 5, Issue 9, Pages 21

Collinear activation of Hoxb genes during gastrulation is linked to mesoderm cell ingression
Tadahiro Iimura ¹ and Olivier Pourquie ^1
1 Howard Hughes Medical Institute and Stowers Institute for Medical Research, 1000 E. 50th Street, Kansas City, Missouri 64110, USA
Nature, Volume 442, Number 7102, Pages 568-571, 3 August 2006

In vivo electroporation in the embryonic mouse central nervous system
Tetsuichiro Saito ¹ (E-mail: tesaito@faculty.chiba-u.jp)
¹ Department of Developmental Biology, Graduate School of Medicine Chiba University, Chiba 260-8670, Japan
Nature Protocols, Volume 1, Number 3, Pages 1552-1558, 2006

Chx10 is required to block photoreceptor differentiation but is dispensable for progenitor proliferation in the postnatal retina
Izzy Livne-bar ^{1, 2}, Marek Pacal ^{1, 2, 4}, Melissa C. Cheung ^{1, 2}, Mark Hankin ⁵, Judy Trogadis ^{1, 2}, Danian Chen ^{1, 2}, Kimberley M. Dorval ^{1, 2, 4} and Rod Bremner ^{1, 2, 3, 4} (E-mail: rbremner@uhnres.utoronto.ca)
¹ Toronto Western Research Institute, University Health Network
² Vision Science Research Program, University of Toronto, Toronto, ON, Canada M5T 2S8
³ Departments of Ophthalmology and Vision Science, University of Toronto, Toronto, ON, Canada M5T 2S8
⁴ Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada M5T 2S8
⁵ Department of Anatomy and Neurobiology, Medical College of Ohio, Toledo, OH 43614
PNAS (Proceedings of the National Academy of Sciences of the United States of America), Volume 103, Number 13, Pages 4988-4993, 28 Mar 2006

Analysis on the Molecular Species and Concentration of Circulating ADAMTS13 in Blood
Kenji Soejima ¹ (E-mail: soejima@kaketsuken.or.jp), Hitomi Nakamura ¹, Masaki Hirashima ¹, Wataru Morikawa ¹, Chikateru Nozaki ¹ and Tomohiro Nakagaki ^1
1 Research Department 1, The Chemo-Sero-Therapeutic Research Institute, Kyokushikawabe, Kikuchi, Kumamoto 869-1298
The Journal of Biochemistry, Volume 139, Issue 1, Pages 147-154, January 2006

Mouse Disabled1 (DAB1) Is a Nucleocytoplasmic Shuttling Protein
Takao Honda ¹ and Kazunori Nakajima ^{1, 2} (E-mail: kazunori@sc.itc.keio.ac.jp)
¹ Department of Anatomy, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
² Department of Molecular Neurobiology, Institute of DNA Medicine, Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan
JBC (The Journal of Biological Chemistry), Volume 281, Issue 50, Pages 38951-38965, 15 December 2006

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
Hajime Kanda ¹, Sanshiro Tateya ¹, Yoshikazu Tamori ¹ (E-mail: tamori@med.kobe-u.ac.jp), Ko Kotani ¹, Ken-ichi Hiasa ², Riko Kitazawa ³, Sohei Kitazawa ³, Hitoshi Miyachi ⁴, Sakan Maeda ³, Kensuke Egashira ² and Masato Kasuga ^1
1 Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
² Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
³ Department of Biomedical Informatics, Kobe University Graduate School of Medicine, Kobe, Japan
⁴ Laboratory for Animal Resources and Genetic Engineering, Center for Developmental Biology (CDB), Institute of Physical and Chemical Research (RIKEN), Kobe, Japan
JCI (The Journal of Clinical Investigation), Volume 116, Issue 6, Pages 1494-1505, June 2006

VEGF 164 gene transfer by electroporation improves diabetic sensory neuropathy in mice
Tatsufumi Murakami ¹ (E-mail: tatsum@med.kawasaki-m.ac.jp), Makiko Arai ², Yoshihide Sunada ¹, Akihiro Nakamura ^2
1 Division of Neurology, Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Japan
² Department of Clinical Pharmacy, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Japan
The Journal of Gene Medicine, Volume 8, Issue 6, Pages 773-781, July 2006

Radial Migration of Superficial Layer Cortical Neurons Controlled by Novel Ig Cell Adhesion Molecule MDGA1
Akihide Takeuchi ¹ and Dennis D. M. O'Leary ^1
1 Molecular Neurobiology Laboratory, The Salk Institute, La Jolla, California 92037, USA
The Journal of Neuroscience, Volume 26, Issue 17, Pages 4460-4464, 26 April 2006

Necdin Promotes GABAergic Neuron Differentiation in Cooperation with Dlx Homeodomain Proteins
Takaaki Kuwajima ¹, Isao Nishimura ¹ and Kazuaki Yoshikawa ¹ (E-mail: yoshikaw@protein.osaka-u.ac.jp)
¹ Laboratory of Regulation of Neuronal Development, Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan
The Journal of Neuroscience, Volume 26, Issue 20, Pages 5383-5392, 17 May 2006

Brain-Derived Neurotrophic Factor Participates in Determination of Neuronal Laminar Fate in the Developing Mouse Cerebral Cortex
Hidefumi Fukumitsu ¹, Masanari Ohtsuka ¹, Rina Murai ¹, Hiroyuki Nakamura ², Kazuo Itoh ² and Shoei Furukawa ¹ (E-mail: furukawa@gifu-pu.ac.jp)
¹ Laboratory of Molecular Biology, Gifu Pharmaceutical University, Gifu 502-8585, Japan
² Department of Morphological Neuroscience, Gifu University Graduate School of Medical Science, Gifu 501-1194, Japan
The Journal of Neuroscience, Volume 26, Issue 51, Pages 3218-13230, 20 December 2006

Gene Expression Analysis of Ectopic Bone Formation Induced by Electroporatic Gene Transfer of BMP4
Satoshi Kotajima ¹, Koshi N. Kishimoto ¹, Munenori Watanuki ¹, Masahito Hatori ¹ and Shoichi Kokubun ^1
1 Department of Orthopaedic surgery, Tohoku University School of Medicine, Sendai, Japan
Upsala Journal of Medical Sciences, Volume 111, Number 2, Pages 231-242, 2006

Multivalent DNA vaccine protects mice against pulmonary infection caused by Pseudomonas aeruginosa
Sukumar Saha ¹, Fumihiko Takeshita ¹, Shin Sasaki ¹, Tomoko Matsuda ¹, Toshiyuki Tanaka ¹, Miyuki Tozuka ¹, Keiko Takase ¹, Tetsuya Matsumoto ², Katsuji Okuda ³, Norihisa Ishii ⁴, Keizo Yamaguchi ², Dennis M. Klinman ⁵, Ke-Qin Xin ¹, Kenji Okuda ¹ (E-mail: kokuda@med.yokohama-cu.ac.jp)
¹ Department of Molecular Biodefense Research, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan
² Department of Microbiology, Toho University School of Medicine, Tokyo 143-0015, Japan
³ Department of Microbiology, Tokyo Dental University, Chiba 261-0011, Japan
⁴ Department of Bioregulation, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo 189-0002, Japan
⁵ Section of Retroviral Immunology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Vaccine, Volume 24, Issues 37-39, Pages 6240-6249, 11 September 2006

[2005]
Production of research-grade antibody by in vivo electroporation of DNA-encoding target protein
Fumiaki Okahara ^{1, 2}, Kouichi Itoh ^{1, 3}, Michihiro Ebihara ⁴, Masao Kobayashi ⁴, Hiroki Maruyama ⁵, Yasunori Kanaho ¹ and Tomohiko Maehama ¹ (E-mail: tmaehama@rinshoken.or.jp)
¹ Department of Pharmacology, Tokyo Metropolitan Institute of Medical Science, Tokyo 113-8613, Japan
² Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, Tokyo 192-0397, Japan
³ Laboratory of Molecular Pharmacology, Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences at Kagawa Campus, Tokushima Bunri University, Kagawa 769-2193, Japan
⁴ Division of Biochemistry, BEX Co. Ltd., Tokyo 173-0004, Japan
⁵ Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8120, Japan
Analytical Biochemistry, Volume 336, Issue 1, Pages 138-140, 1 January 2005

Use of local electroporation enhances methotrexate effects with minimum dose in adjuvant-induced arthritis
Masahiro Tada ¹ (E-mail: m-tada@med.osaka-cu.ac.jp), Kentaro Inui ¹, Tatsuya Koike ¹ and Kunio Takaoka ^1
1 Osaka City University, Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan
Arthritis & Rheumatism, Volume 52, Issue 2, Pages 637-641, February 2005

Electro-transfer of small interfering RNA ameliorated arthritis in rats
Atsuo Inoue ¹, Kenji A. Takahashi ¹ (E-mail: t-keji@mbox.kyoto-inet.or.jp), Osam Mazda ², Ryu Terauchi ¹, Yuji Arai ¹, Tsunao Kishida ^{2, 3}, Masaharu Shin-Ya ², Hidetsugu Asada ², Toru Morihara ¹, Hitoshi Tonomura ¹, Suzuyo Ohashi ¹, Yoshiteru Kajikawa ¹, Yutaka Kawahito ⁴, Jiro Imanishi ², Mitsuhiro Kawata ⁵, Toshikazu Kubo ^1
1 Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
² Department of Microbiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
³ Louis Pasteur Center for Medical Research, Kyoto 606-8225, Japan
⁴ Department of Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
⁵ Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan
Biochemical and Biophysical Research Communications, Volume 336, Issue 3, Pages 903-908, 28 October 2005

G Protein betagamma Subunits and AGS3 Control Spindle Orientation and Asymmetric Cell Fate of Cerebral Cortical Progenitors
Kamon Sanada ¹ and Li-Huei Tsai ^{1, 2} (E-mail: li-huei_tsai@hms.harvard.edu)
¹ Department of Pathology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115
² Howard Hughes Medical Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115
Cell, Volume 122, Issue 1, Pages 119-131, 15 July 2005

XAGE-1 Expression in Non-Small Cell Lung Cancer and Antibody Response in Patients
Kazuhiko Nakagawa ^{1, 2}, Yuji Noguchi ¹, Akiko Uenaka ¹, Shuichiro Sato ¹, Hideo Okumura ^{1, 2}, Motoyuki Tanaka ¹, Michihide Shimono ¹, Ali Mohamed Ali Eldib ¹, Toshiro Ono ¹, Nobuya Ohara ³, Tadashi Yoshino ³, Kazuki Yamashita ⁴, Tsukasa Tsunoda ⁴, Motoi Aoe ², Nobuyoshi Shimizu ² and Eiichi Nakayama ¹ (E-mail: nakayama@md.okayama-u.ac.jp)
¹ Departments of Immunology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
² Departments of Oncology and Thoracic Surgery Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
³ Departments of Pathology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
⁴ Department of Surgery, Division of Gastroenterology, Kawasaki Medical School, Kurashiki, Japan
Clinical Cancer Research, Volume 11, Issue 15, Pages 5496-5503, 1 August 2005

Progenitors resume generating neurons after temporary inhibition of neurogenesis by Notch activation in the mammalian cerebral cortex
Ken-ichi Mizutani ¹ and Tetsuichiro Saito ^{1, *} (E-mail: tesaito@frontier.kyoto-u.ac.jp)
¹ Department of Development and Differentiation, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan
^* Present address: Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan
Development, Volume 132, Issue 6, Pages 1295-1304, March 2005

Commissural neuron identity is specified by a homeodomain protein, Mbh1, that is directly downstream of Math1
Rie Saba ¹, Jane E. Johnson ² and Tetsuichiro Saito ¹ (E-mail: tesaito@frontier.kyoto-u.ac.jp)
¹ Department of Development and Differentiation, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan
² Center for Basic Neuroscience, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9111, USA
Development, Volume 132, Issue 9, Pages 2147-2155, May 2005

Notch signaling functions as a binary switch for the determination of glandular and luminal fates of endodermal epithelium during chicken stomach development
Yoshimasa Matsuda ¹, Yoshio Wakamatsu ², Jun Kohyama ³, Hideyuki Okano ³, Kimiko Fukuda ¹ and Sadao Yasugi ¹ (E-mail: yasugi-sadao@c.metro-u.ac.jp)
¹ Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, 1-1 Minamiohsawa, Hachiohji, Tokyo 192-0397, Japan
² Department of Developmental Neurobiology, Graduate School of Medicine, Tohoku University, Sendai, Miyagi 980-8575, Japan
³ Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan
Development, Volume 132, Issue 12, Pages 2783-2793, June 2005

Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor
Atsushi Sawada ¹, Yuriko Nishizaki ², Hiroko Sato ¹, Yukari Yada ¹, Rika Nakayama ³, Shinji Yamamoto ¹, Noriyuki Nishioka ¹, Hisato Kondoh ² and Hiroshi Sasaki ¹ (E-mail: sasaki@cdb.riken.jp),
¹ Laboratory for Embryonic Induction, RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan
² Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan
³ Laboratory for Animal Resources and Genetic Engineering (LARGE), RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan
Development, Volume 132, Issue 21, Pages 4719-4729, November 2005

Ex ovo electroporation for gene transfer into older chicken embryos
Jiankai Luo ¹ (E-mail: tluo@mti.uni-jena.de) and Christoph Redies ^1
1 Institute of Anatomy I, Friedrich Schiller University, Jena, Germany
Developmental Dynamics, Volume 233, Issue 4, Pages 1470-1477, August 2005

Regulation of Slug transcription in embryonic ectoderm by beta-catenin-Lef/Tcf and BMP-Smad signaling
Daisuke Sakai ¹, Yasuko Tanaka ², Yukinori Endo ¹, Noriko Osumi ¹, Harumasa Okamoto ² and Yoshio Wakamatsu ³ (E-mail: wakasama@mail.tains.tohoku.ac.jp)
¹ Center for Translational and Advanced Animal Research on Human Diseases, Division of Developmental Neuroscience, Graduate School of Medicine, Tohoku University, Sendai, Miyagi 980-8575, Japan
² AIST, Tsukuba, Japan
³ Department of Developmental Neurobiology, Graduate School of Medicine, Tohoku University, Sendai, Miyagi 980-8575, Japan
Development, Growth & Differentiation, Volume 47, Issue 7, Pages 471-482, September 2005

Birth-date-dependent segregation of the mouse cerebral cortical neurons in reaggregation cultures
Itsuki Ajioka ^{1, 2} and Kazunori Nakajima ^{1, 2, 3} (E-mail: kazunori@sc.itc.keio.ac.jp)
¹ Department of Anatomy, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
² Department of Molecular Neurobiology, Institute of DNA Medicine, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo 105-8461, Japan
³ Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Corporation (JST), 4-1-8 Honmachi, Kawaguchi, Saitama 332-0012, Japan
European Journal of Neuroscience, Volume 22, Issue 2, Pages 331-342, July 2005

FGF8 initiates inner ear induction in chick and mouse
Raj K. Ladher ^{1, 2, *}, (E-mail raj-ladher@cdb.riken.go.jp), Tracy J. Wright ^{4, *}, Anne M. Moon ^{2, 5}, Suzanne L. Mansour ^{2, 4} and Gary C. Schoenwolf ^{2, 3
1} Sensory Development, Riken Center for Developmental Biology, Chuo-ku, Kobe 650-0047, Japan
² Department of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, Utah 84132-3401, USA
³ Department of Children's Health Research Center, University of Utah School of Medicine, Salt Lake City, Utah 84132-3401, USA
⁴ Department of Human Genetics, University of Utah, Salt Lake City, Utah 84112-5330, USA
⁵ Department of Program in Human Molecular Biology and Genetics, University of Utah, Salt Lake City, Utah 84112-5330, USA
^* These authors contributed equally to the study
Genes & Development, Volume 19, Issue 5, Pages 603-613, 1 March 2005

Generation of antitumor immunity against large colon tumors by repeated runs of electrochemotherapy
Yoshio Gunji ¹ (E-mail: gunjim9@faculty.chiba-u.jp), Masaya Uesato ¹, Shinichi Miyazaki ¹, Hideaki Shimada ¹, Hisahiro Matsubara ¹, Yoshihiro Nabeya ¹, Keiji Kouda ¹, Harufumi Makino ¹, Teruo Kouzu ¹ and Takenori Ochiai ^1
1 Department of Frontier Surgery (M9), Graduate School of Medicine, Chiba University School of Medicine, Chiba, Japan
Hepatogastroenterology, Volume 52, Number 63, Pages 770-774, May-June 2005

The Pax6 isoform bearing an alternative spliced exon promotes the development of the neural retinal structure
Noriyuki Azuma ^{1, 2} (E-mail: azuma-n@ncchd.go.jp), Keiko Tadokoro ², Astuko Asaka ², Masao Yamada ², Yuki Yamaguchi ³, Hiroshi Handa ³, Satsuki Matsushima ⁴, Takashi Watanabe ⁴, Shinichi Kohsaka ⁵, Yasuyuki Kida ⁶, Tomoki Shiraishi ⁶, Toshihiko Ogura ⁶, Kenji Shimamura ^{7, 8} and Masato Nakafuku ^{7, 9
1} Department of Ophthalmology, National Center for Child Health and Development, Tokyo 157-8535, Japan
² Department of Genetics, National Research Institute for Child Health and Development, Tokyo 154-8567, Japan
³ Department of Biological Information, Tokyo Institute of Technology, Graduate School of Bioscience and Biotechnology, Yokohama, 226-8501, Japan
⁴ Department of Laboratory Medicine, Kyorin University School of Medicine, Tokyo 181-8611, Japan
⁵ National Institute of Neuroscience, Tokyo 187-8502, Japan
⁶ Department of Developmental Neurobiology, Institute of Development, Aging and Cancer, Sendai 980-8575, Japan
⁷ Department of Neuroscience, University of Tokyo Graduate School of Medicine, Tokyo 113-0033, Japan
⁸ Division of Morphogenesis, Department of Embroyogenesis, Institute of Molecular Embryology and Genetics, Kumamoto University, Honjo 2-2-1, Kumamoto 860-0811, Japan
⁹ Division of Developmental Biology, Cincinnati Children's Hospital Research Foundation, Cincinnati, OH 45229, USA
Human Molecular Genetics, Volume 14, Number 6, Pages 735-745, 15 March 2005

Transdifferentiation of the retinal pigment epithelia to the neural retina by transfer of the Pax6 transcriptional factor
Noriyuki Azuma ^{1, 2} (E-mail: azuma-n@ncchd.go.jp), Keiko Tadokoro ², Astuko Asaka ², Masao Yamada ², Yuki Yamaguchi ³, Hiroshi Handa ³, Satsuki Matsushima ⁴, Takashi Watanabe ⁴, Yasuyuki Kida ⁵, Toshihiko Ogura ⁵, Masaaki Torii ⁶, Kenji Shimamura ^{6, 7} and Masato Nakafuku ^{6, 8
1} Department of Ophthalmology, National Center for Child Health and Development, Tokyo 157-8535, Japan
² Department of Genetics, National Research Institute for Child Health and Development, Tokyo 154-8567, Japan
³ Department of Biological Information, Tokyo Institute of Technology, Graduate School of Bioscience and Biotechnology, Yokohama 226-8501, Japan
⁴ Department of Clinical Research Medicine, Kyorin University School of Medicine, Tokyo 181-8611, Japan
⁵ Department of Developmental Neurobiology, Institute of Development, Aging and Cancer, Sendai 980-8575, Japan
⁶ Department of Neuroscience, University of Tokyo Graduate School of Medicine, Tokyo 113-0033, Japan
⁷ Division of Morphogenesis, Department of Embryogenesis, Institute of Molecular Embryology and Genetics, Kumamoto University, Honjo 2-2-1, Kumamoto 860-0811, Japan
⁸ Division of Developmental Biology, Cincinnati Children's Hospital Research Foundation, Cincinnati, OH 45229, USA
Human Molecular Genetics, Volume 14, Number 8, Pages 1059-1068, 15 April 2005

Immune deficiency enhances expression of recombinant human antibody in mice after nonviral in vivo gene transfer
Kohji Kitaguchi ¹, Mikako Toda ¹, Masataka Takekoshi ², Fumiko Maeda ², tatsuo Muramatsu ¹ and Atsushi Murai ^1
1 Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601
² Department of Molecular Life Science, Tokai University School of Medicine, Bohseidai, Isehara 259-1193, Japan
International Journal of Molecular Medicine, Volume 16, Number 4, Pages 683-688, October 2005

Mutated-leptin gene transfer induces increases in body weight by electroporation and hydrodynamics-based gene delivery in mice
Lan Xiang ¹, Atsushi Murai ¹