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Featured Device

0
Product Code: SONIDEL SP100

Desc:Sonoporator
Applic:(hover for application)Application:
  • Delivery of plasmids to cells and tissues for gene therapy-based applications and studies.
  • Delivery of nucleic acids such as siRNA, RNAi etc. to cells and tissues for studies on control of gene expression/gene therapy.
  • Delivery of cancer chemotherapeutic agents to impermeable target cells/tissues.
  • Delivery of agents to cells to study metabolic effects.


Featured Electrode



Product Code: CUY261-0.8

Application:
Electrodes for Electroporation
Description:
Needle electrode for tissue 0.8mmf, Length 60mm, Tip 10mm

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Electroporation-mediated gene transfer in the adult rat brain

Electroporation-mediated gene transfer in the adult Rat Brain


NEPA21 / CUY21 Applications

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[Brain] Electroporation-mediated gene transfer in the adult rat brain

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EGFP expression in the medial preoptic nuclei of a female rat EGFP-positive cells

Figure A: EGFP expression in the medial preoptic nuclei of a female rat examined 4 days after bilateral electroporation at 10 weeks of age.

(An asterisk indicates the trace of the positioning of the electrode)

Figure B: EGEP-positive cells (high magnification of Fig. A using a 60x objective lens)  EGFP fluorescent signals are observed in the perikarya.

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Estrogen receptor α immunoreactivity in the medial preoptic nuclei and the periventricular nuclei of an adult female rat Estrogen receptorα-positive cells

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Figure C: Estrogen receptor α immunoreactivity in the medial preoptic nuclei and the periventricular nuclei of an adult female rat.

3V: third ventricle

Figure D: Estrogen receptor α-positive cells (high magnification of Fig. C using a 60x objective lens).  Estrogen receptor α immunoreactivity is prominent in the nuclei.

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Center for Advanced Oral Medicine, Hokkaido University Hospital; Tetsuo Shirakawa

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