Electrochemotherapy for digital chondrosarcoma
Electrochemotherapy for digital chondrosarcoma
NEPA21 / CUY21 Applications |
[Cancer Therapy] Electrochemotherapy for digital chondrosarcoma.
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a. Proximal phalanx of the middle finger is swollen. b. Expanding radiolucent mass in the proximal phalangeal bone. c. No recurrence was seen even 3 years after treatment.
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Biopsy specimen. a) Cells varying in size and shape with nuclear atypia and multivesicular vacuolation of cytoplasm. b) Two weeks after electrochemotherapy, histological analysis of core needle biopsies revealed 90% tumor cell necrosis
H&E x 200 |
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Electrode and electroporation. a. Stainless steel 3cm x 5cm electrodes. b. Electroporation with two parallel electrodes placed on opposite sides of the tumor
Resistance Measurement: 245±101Ω Voltage: 150V (Electric field strength: 50/cm) Current: 1.1±0.5A Pulses:
4 pulses of 250ms (On: 50ms, Off: 200ms) Or 6 pulses of 167ms (On: 50ms, Off: 117ms) |
Gross and microscopic findings of the resected tumor. a) Gross appearance of marginally resected tumor. b) Cut surface. c) Microphotograph of the central portion of the tumor (area c in panel b). d) Peripheral region (area d in panel b).
H&E x 200
A histological study of the resected tumor showed necrosis at the tumor margin. |
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