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Featured Device

0
Product Code: SONIDEL SP100

Desc:Sonoporator
Applic:(hover for application)Application:
  • Delivery of plasmids to cells and tissues for gene therapy-based applications and studies.
  • Delivery of nucleic acids such as siRNA, RNAi etc. to cells and tissues for studies on control of gene expression/gene therapy.
  • Delivery of cancer chemotherapeutic agents to impermeable target cells/tissues.
  • Delivery of agents to cells to study metabolic effects.


Featured Electrode



Product Code: CUY5000P0.5

Application:
Electrodes for Electro Cell Fusion
Description:
Platinum wire electrodes on petridish, 0.5mm gap

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Cancer Therapy & CUY21

Electroporative Gene Delivery into Tumours using the CUY21 Electroporation System


The CUY21 EDIT and CUY21 SC electroporator range has been used to perform electro-chemotherapy on human skin cancer as a clinical test.  Kindly note the article: ‘Electrochemotherapy for digital chondrosarcoma’. In this article, bleomycine is introduced into the tumor by electroporation.

The CUY21 electroporation system has also been used to perform electroporation on hepatocellular carcinoma (HCC).  Kindly note the paper titled: Electroporation-mediated Interleukin-12 Gene Therapy for Hepatocellular carcinoma in Mice Models.  In this paper, genes which express IL-12 are transfected into HCC and the growth of HCC is prohibited.  In this paper, while a CUY560-5 electrode is used, we would, however, recommend the CUY560-5-0.3 electrode.

View Technical Drawing of CUY560P5-0.3 Electrode


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